{ "Entity": { "Name": "lobelanidine", "SMILES": "CN1C(CCCC1CC(C2=CC=CC=C2)O)CC(C3=CC=CC=C3)O", "Accession": "BRD-A59215453", "InChI_key": "OWGJQNXIWMMDTH-UHFFFAOYSA-N" }, "Associations": [ { "Term": [ { "Name": ">= 4 H", "Accession": "PubChem0" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 8 H", "Accession": "PubChem1" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 16 H", "Accession": "PubChem2" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 C", "Accession": "PubChem9" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 4 C", "Accession": "PubChem10" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 8 C", "Accession": "PubChem11" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 16 C", "Accession": "PubChem12" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 N", "Accession": "PubChem14" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 O", "Accession": "PubChem18" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 O", "Accession": "PubChem19" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 any ring size 6", "Accession": "PubChem178" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic carbon-only ring size 6", "Accession": "PubChem179" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic nitrogen-containing ring size 6", "Accession": "PubChem180" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic heteroatom-containing ring size 6", "Accession": "PubChem181" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 any ring size 6", "Accession": "PubChem185" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 saturated or aromatic carbon-only ring size 6", "Accession": "PubChem186" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 3 any ring size 6", "Accession": "PubChem192" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 aromatic ring", "Accession": "PubChem255" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 aromatic rings", "Accession": "PubChem257" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-H", "Accession": "PubChem283" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C", "Accession": "PubChem284" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N", "Accession": "PubChem285" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-O", "Accession": "PubChem286" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-H", "Accession": "PubChem308" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)", "Accession": "PubChem332" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~C)", "Accession": "PubChem333" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~H)(~N)", "Accession": "PubChem338" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~H)(~O)", "Accession": "PubChem339" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~N)", "Accession": "PubChem340" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~O)", "Accession": "PubChem341" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)", "Accession": "PubChem344" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)(~N)", "Accession": "PubChem345" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)(~O)", "Accession": "PubChem346" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~N)", "Accession": "PubChem351" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~O)", "Accession": "PubChem352" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:C)", "Accession": "PubChem355" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:C)(:C)", "Accession": "PubChem356" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(~N)", "Accession": "PubChem365" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(~O)", "Accession": "PubChem366" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(:C)", "Accession": "PubChem370" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(:C)(:C)", "Accession": "PubChem371" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(~H)(~H)", "Accession": "PubChem374" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:C)(:C)", "Accession": "PubChem384" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)", "Accession": "PubChem390" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)(~C)", "Accession": "PubChem391" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O(~C)(~H)", "Accession": "PubChem406" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C", "Accession": "PubChem416" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-C)(=C)", "Accession": "PubChem430" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-H)(=C)", "Accession": "PubChem434" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(=C)", "Accession": "PubChem441" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-H)(=C)", "Accession": "PubChem446" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C=C", "Accession": "PubChem470" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C=C", "Accession": "PubChem490" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-C=C-[#1]", "Accession": "PubChem516" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C-C:C", "Accession": "PubChem520" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C=C-C", "Accession": "PubChem524" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-[#1]", "Accession": "PubChem540" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C:C", "Accession": "PubChem548" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C:C", "Accession": "PubChem552" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C-C-C", "Accession": "PubChem556" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C-C=C", "Accession": "PubChem564" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C-C", "Accession": "PubChem570" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-C-O-[#1]", "Accession": "PubChem571" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C=C", "Accession": "PubChem573" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C:C-C", "Accession": "PubChem574" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C:C-C:C", "Accession": "PubChem578" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C", "Accession": "PubChem582" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C=C-C", "Accession": "PubChem584" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-C-C", "Accession": "PubChem592" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C-C-C", "Accession": "PubChem595" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-C-C=C-[#1]", "Accession": "PubChem599" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C:C:C-C", "Accession": "PubChem603" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C:C", "Accession": "PubChem608" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-C-C", "Accession": "PubChem613" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-O-[#1]", "Accession": "PubChem617" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C-C-C:C", "Accession": "PubChem618" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C=C-C", "Accession": "PubChem619" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C:C-C", "Accession": "PubChem634" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C", "Accession": "PubChem637" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-N", "Accession": "PubChem638" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C-C-C-C", "Accession": "PubChem640" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C=C", "Accession": "PubChem641" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C:C", "Accession": "PubChem655" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-N-C-C", "Accession": "PubChem656" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C=C-C-C", "Accession": "PubChem660" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C=C-C=C", "Accession": "PubChem664" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C-C-O-[#1]", "Accession": "PubChem667" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C:C-C-C", "Accession": "PubChem668" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C=C-C:C", "Accession": "PubChem677" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C=C-C", "Accession": "PubChem678" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C-C", "Accession": "PubChem679" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C", "Accession": "PubChem680" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-C-C-C", "Accession": "PubChem683" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C-C-C", "Accession": "PubChem688" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C-C", "Accession": "PubChem689" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C-C-C-C", "Accession": "PubChem696" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C-C(C)-C", "Accession": "PubChem697" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C-C-C", "Accession": "PubChem698" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C(C)-C-C", "Accession": "PubChem708" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C(C)-C-C-C", "Accession": "PubChem709" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C(C)-C-C", "Accession": "PubChem710" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "integrin binding (GO:0005178)", "Accession": "GO:0005178" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "SLC6A8", "Accession": "6535" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSMB", "Accession": "4477" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DDX3Y", "Accession": "8653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SFN", "Accession": "2810" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NTS", "Accession": "4922" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYTIP", "Accession": "9595" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALML5", "Accession": "51806" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HES1", "Accession": "3280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRKD3", "Accession": "23683" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MUC5B", "Accession": "727897" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COCH", "Accession": "1690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LTF", "Accession": "4057" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ID2", "Accession": "3398" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SOX9", "Accession": "6662" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EIF1AY", "Accession": "9086" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DPP4", "Accession": "1803" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CA12", "Accession": "771" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LCP1", "Accession": "3936" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD24", "Accession": "100133941" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DKK1", "Accession": "22943" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF586", "Accession": "54807" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HMGCS1", "Accession": "3157" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LY6E", "Accession": "4061" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCOLCE2", "Accession": "26577" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IFI6", "Accession": "2537" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RALGDS", "Accession": "5900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMPRSS3", "Accession": "64699" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PXMP2", "Accession": "5827" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB2A", "Accession": "7280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABCG2", "Accession": "9429" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GABRP", "Accession": "2568" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TGFBR3", "Accession": "7049" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRABP1", "Accession": "1381" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRABP2", "Accession": "1382" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AQP3", "Accession": "360" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL14", "Accession": "9547" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ENPP2", "Accession": "5168" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GATA3", "Accession": "2625" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB3", "Accession": "10381" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HOPX", "Accession": "84525" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IRF7", "Accession": "3665" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HPGD", "Accession": "3248" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MARCKSL1", "Accession": "65108" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TM4SF1", "Accession": "4071" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LMNA", "Accession": "4000" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EZR", "Accession": "7430" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGG", "Accession": "2266" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TM4SF20", "Accession": "79853" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALML3", "Accession": "810" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NES", "Accession": "10763" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP2", "Accession": "1844" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JUND", "Accession": "3727" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CADM1", "Accession": "23705" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SELENOP", "Accession": "6414" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD59", "Accession": "966" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL6A2", "Accession": "1292" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOLR1", "Accession": "2348" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "WWP1", "Accession": "11059" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPM6B", "Accession": "2824" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HMG20B", "Accession": "10362" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TYRP1", "Accession": "7306" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KLK5", "Accession": "25818" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SERPINB5", "Accession": "5268" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HEPH", "Accession": "9843" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CLDN3", "Accession": "1365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "H2BC12", "Accession": "85236" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT14", "Accession": "3861" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FLG", "Accession": "2312" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCR7", "Accession": "1236" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IKZF1", "Accession": "10320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT6B", "Accession": "3854" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RRS1", "Accession": "23212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRYAB", "Accession": "1410" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MYBL1", "Accession": "4603" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "F13A1", "Accession": "2162" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM158", "Accession": "25907" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TFAP2C", "Accession": "7022" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IER5", "Accession": "51278" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BCL3", "Accession": "602" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "S100A10", "Accession": "6281" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HTATIP2", "Accession": "10553" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCEL", "Accession": "8796" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPRR1A", "Accession": "6698" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPRR1B", "Accession": "6699" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZIC1", "Accession": "7545" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DSG3", "Accession": "1830" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB4B", "Accession": "10383" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT16", "Accession": "3868" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC42SE1", "Accession": "56882" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TENT5A", "Accession": "55603" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SERPINB3", "Accession": "6317" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP5", "Accession": "1847" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRIM29", "Accession": "23650" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LYPD3", "Accession": "27076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TCF4", "Accession": "6925" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FBLN1", "Accession": "2192" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "H1-2", "Accession": "3006" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CEACAM5", "Accession": "1048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCRG1", "Accession": "11341" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGB", "Accession": "2244" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TWIST1", "Accession": "7291" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KLK6", "Accession": "5653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ATP6V1D", "Accession": "51382" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MDFIC", "Accession": "29969" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RRAD", "Accession": "6236" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HDDC2", "Accession": "51020" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JUP", "Accession": "3728" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COLEC12", "Accession": "81035" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTN", "Accession": "5764" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NELL2", "Accession": "4753" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GJA1", "Accession": "2697" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CST1", "Accession": "1469" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LGALS3", "Accession": "3958" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRPS1", "Accession": "7227" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MMP10", "Accession": "4319" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJB2", "Accession": "3300" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DSG1", "Accession": "1828" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEAT1", "Accession": "283131" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NFATC3", "Accession": "4775" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPBP", "Accession": "5473" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZFP36L2", "Accession": "678" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LRRN3", "Accession": "54674" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC9A3R1", "Accession": "9368" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LEF1", "Accession": "51176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DCN", "Accession": "1634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCOLCE", "Accession": "5118" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACTA1", "Accession": "58" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ESR1", "Accession": "2099" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DIO2", "Accession": "1734" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC27A2", "Accession": "11001" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRD", "Accession": "6964" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC1A1", "Accession": "6505" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RCAN1", "Accession": "1827" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MX1", "Accession": "4599" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DMAC2L", "Accession": "27109" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TPPP3", "Accession": "51673" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RUNX3", "Accession": "864" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "B4GALT4", "Accession": "8702" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBE2M", "Accession": "9040" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRIP1", "Accession": "1396" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL1A1", "Accession": "1277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL2A1", "Accession": "1280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCSK1N", "Accession": "27344" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPIC", "Accession": "5480" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IVNS1ABP", "Accession": "10625" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SEMA6A", "Accession": "57556" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AGT", "Accession": "183" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PMEL", "Accession": "6490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GRIA2", "Accession": "2891" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTER", "Accession": "9317" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDHR5", "Accession": "53841" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TFDP2", "Accession": "7029" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AMDHD2", "Accession": "51005" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AHNAK", "Accession": "79026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DENND1B", "Accession": "163486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VPS28", "Accession": "51160" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MMP11", "Accession": "4320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APOB", "Accession": "338" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABHD11", "Accession": "83451" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DHRS11", "Accession": "79154" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCSK6", "Accession": "5046" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A6", "Accession": "9120" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRDV3", "Accession": "28516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FZD7", "Accession": "8324" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BSG", "Accession": "682" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TEX10", "Accession": "54881" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "INSM1", "Accession": "3642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APOA2", "Accession": "336" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NPR3", "Accession": "4883" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOXG1", "Accession": "2290" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TM4SF4", "Accession": "7104" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ATP5F1C", "Accession": "509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRCT1", "Accession": "54544" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PEBP1", "Accession": "5037" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EIF4B", "Accession": "1975" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SRC", "Accession": "6714" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGA", "Accession": "2243" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CHMP4A", "Accession": "29082" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HS2ST1", "Accession": "9653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ASMTL", "Accession": "8623" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRIP2", "Accession": "1397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TSNAX", "Accession": "7257" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "WFS1", "Accession": "7466" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT1", "Accession": "3848" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALML4", "Accession": "91860" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TBC1D31", "Accession": "93594" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SMYD2", "Accession": "56950" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "P4HTM", "Accession": "54681" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC6A14", "Accession": "11254" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ECI1", "Accession": "1632" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LY6D", "Accession": "8581" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HGD", "Accession": "3081" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RAB25", "Accession": "57111" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPRY2", "Accession": "10253" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAPK6", "Accession": "5597" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPINK5", "Accession": "11005" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DDAH1", "Accession": "23576" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RBM38", "Accession": "55544" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HBD", "Accession": "100187828" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MX2", "Accession": "4600" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APOC3", "Accession": "345" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SI", "Accession": "6476" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APOA1", "Accession": "335" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLEC", "Accession": "5339" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACSS3", "Accession": "79611" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GLUD1", "Accession": "2746" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALAS2", "Accession": "212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCSK5", "Accession": "5125" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NFKB2", "Accession": "4791" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIP4K2C", "Accession": "79837" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLA2G4A", "Accession": "5321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF551", "Accession": "90233" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPAA1", "Accession": "8733" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EPHX2", "Accession": "2053" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SMAP1", "Accession": "60682" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BCKDHB", "Accession": "594" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FNDC3B", "Accession": "64778" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PPP2R5E", "Accession": "5529" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYH10", "Accession": "4628" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AIDA", "Accession": "64853" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TGFBR2", "Accession": "7048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MXRA7", "Accession": "439921" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEMA3C", "Accession": "10512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GNAS", "Accession": "2778" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FIS1", "Accession": "51024" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAP4K4", "Accession": "9448" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEL1L3", "Accession": "23231" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LTBP2", "Accession": "4053" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCG5", "Accession": "6447" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GUCY1A1", "Accession": "2982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DDIT4", "Accession": "54541" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP1B1", "Accession": "481" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL9", "Accession": "4283" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MT1E", "Accession": "4493" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COTL1", "Accession": "23406" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IDO1", "Accession": "3620" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LCN2", "Accession": "3934" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CDKN1C", "Accession": "1028" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RGS5", "Accession": "8490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HLA-DQA1", "Accession": "3117" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BHLHE41", "Accession": "79365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SOD2", "Accession": "6648" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCTD12", "Accession": "115207" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM47", "Accession": "83604" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNFSF13", "Accession": "8741" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MECOM", "Accession": "2122" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACVR1", "Accession": "90" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CMAHP", "Accession": "8418" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLIPR1", "Accession": "11010" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FBN1", "Accession": "2200" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMBIM1", "Accession": "64114" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MFAP5", "Accession": "8076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FRY", "Accession": "10129" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KMO", "Accession": "8564" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TSPYL5", "Accession": "85453" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLLP", "Accession": "51090" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MT1M", "Accession": "4499" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "APOL3", "Accession": "80833" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSRP1", "Accession": "1465" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGL", "Accession": "3535" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "WFDC2", "Accession": "10406" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNFAIP3", "Accession": "7128" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYO1B", "Accession": "4430" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NR2F2", "Accession": "7026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RARRES1", "Accession": "5918" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SVIL", "Accession": "6840" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH1A1", "Accession": "216" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYH11", "Accession": "4629" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SULF1", "Accession": "23213" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "M6PR", "Accession": "4074" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAV1", "Accession": "857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DIPK1A", "Accession": "388650" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACSL3", "Accession": "2181" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BCHE", "Accession": "590" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FAIM", "Accession": "55179" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CFB", "Accession": "629" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PCDH7", "Accession": "5099" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CANT1", "Accession": "124583" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "H4C3", "Accession": "8364" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TGM2", "Accession": "7052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "APBB2", "Accession": "323" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FLRT2", "Accession": "23768" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MET", "Accession": "4233" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCNMA1", "Accession": "3778" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RRBP1", "Accession": "6238" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP7", "Accession": "3490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAOA", "Accession": "4128" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "VWF", "Accession": "7450" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALCAM", "Accession": "214" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SGK1", "Accession": "6446" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLAAT4", "Accession": "5920" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADGRG6", "Accession": "57211" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RNF167", "Accession": "26001" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CALR", "Accession": "811" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AHCY", "Accession": "191" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IL6ST", "Accession": "3572" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SIRPA", "Accession": "140885" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "THBS1", "Accession": "7057" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCL20", "Accession": "6364" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SMC1A", "Accession": "8243" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEC23A", "Accession": "10484" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ERLIN1", "Accession": "10613" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SORL1", "Accession": "6653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GSTM3", "Accession": "2947" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP1A1", "Accession": "476" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CALD1", "Accession": "800" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CHST15", "Accession": "51363" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NEDD4L", "Accession": "23327" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PNN", "Accession": "5411" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TLR4", "Accession": "7099" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HLA-DQB1", "Accession": "3119" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADGRF5", "Accession": "221395" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAVIN2", "Accession": "8436" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GIMAP4", "Accession": "55303" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AZGP1", "Accession": "563" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LTA4H", "Accession": "4048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RPS21", "Accession": "6227" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LY96", "Accession": "23643" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGKC", "Accession": "3514" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRNP", "Accession": "5621" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FN1", "Accession": "2335" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SRPX", "Accession": "8406" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PXDN", "Accession": "7837" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EFEMP1", "Accession": "2202" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GALNT7", "Accession": "51809" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SH3BP4", "Accession": "23677" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRKAR2B", "Accession": "5577" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MCTP1", "Accession": "79772" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBC1D9", "Accession": "23158" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFI16", "Accession": "3428" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CDK6", "Accession": "1021" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AEBP1", "Accession": "165" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PECAM1", "Accession": "5175" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYOF", "Accession": "26509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RGS4", "Accession": "5999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTGIS", "Accession": "5740" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PBX3", "Accession": "5090" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MTUS1", "Accession": "57509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC1A4", "Accession": "6509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ISL1", "Accession": "3670" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CNPY3", "Accession": "10695" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TPM2", "Accession": "7169" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLAT", "Accession": "5327" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LGALS3BP", "Accession": "3959" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A3", "Accession": "9123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SFRP4", "Accession": "6424" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FKBP1B", "Accession": "2281" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PNMA2", "Accession": "10687" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PPP1R1A", "Accession": "5502" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH1A3", "Accession": "220" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAVIN1", "Accession": "284119" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DHRS2", "Accession": "10202" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BST2", "Accession": "684" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GZMA", "Accession": "3001" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITGAE", "Accession": "3682" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HOXA5", "Accession": "3202" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FXYD5", "Accession": "53827" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGAP29", "Accession": "9411" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNFSF10", "Accession": "8743" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MN1", "Accession": "4330" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GPX1", "Accession": "2876" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ST6GAL1", "Accession": "6480" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CILP", "Accession": "8483" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "H2AZ2", "Accession": "94239" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DMXL2", "Accession": "23312" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MEG3", "Accession": "55384" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TFAP2B", "Accession": "7021" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GNG11", "Accession": "2791" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TCF7L2", "Accession": "6934" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LIMCH1", "Accession": "22998" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CX3CL1", "Accession": "6376" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAPG", "Accession": "822" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH2", "Accession": "217" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AMIGO2", "Accession": "347902" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCN1", "Accession": "3491" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTHLH", "Accession": "5744" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAMLD1", "Accession": "10046" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GBP1", "Accession": "2633" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TAC1", "Accession": "6863" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "H1-0", "Accession": "3005" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NAV3", "Accession": "89795" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SST", "Accession": "6750" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KRT18", "Accession": "3875" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSF2RB", "Accession": "1439" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SNX10", "Accession": "29887" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ABCA1", "Accession": "19" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MMRN1", "Accession": "22915" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NFIB", "Accession": "4781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADAMTS1", "Accession": "9510" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "VAT1", "Accession": "10493" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEPTIN6", "Accession": "23157" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NBL1", "Accession": "4681" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "WARS1", "Accession": "7453" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CIAPIN1", "Accession": "57019" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCNN1A", "Accession": "6337" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RAB13", "Accession": "5872" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "P2RX5", "Accession": "5026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "APOL1", "Accession": "8542" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLAGL1", "Accession": "5325" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAV2", "Accession": "858" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRKCH", "Accession": "5583" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HNRNPC", "Accession": "3183" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GASK1B", "Accession": "51313" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLEC11A", "Accession": "6320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PADI2", "Accession": "11240" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NRP1", "Accession": "8829" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PMEPA1", "Accession": "56937" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MCAM", "Accession": "4162" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RARRES2", "Accession": "5919" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NUPR1", "Accession": "26471" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GUCY1B1", "Accession": "2983" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GRK5", "Accession": "2869" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MT2A", "Accession": "4502" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MSN", "Accession": "4478" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PDE1A", "Accession": "5136" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCPEP1", "Accession": "59342" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PAPOLA", "Accession": "10914" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GBP2", "Accession": "2634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ARL6IP5", "Accession": "10550" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "C2CD2", "Accession": "25966" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITGA4", "Accession": "3676" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FAM171A1", "Accession": "221061" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BCL11A", "Accession": "53335" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLIC4", "Accession": "25932" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ELOVL5", "Accession": "60481" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC43A3", "Accession": "29015" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ICAM2", "Accession": "3384" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "WWTR1", "Accession": "25937" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LDHB", "Accession": "3945" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MBTPS1", "Accession": "8720" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFNGR2", "Accession": "3460" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GZMK", "Accession": "3003" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RNF130", "Accession": "55819" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZFP36L1", "Accession": "677" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJB4", "Accession": "11080" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ASPH", "Accession": "444" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC2A6", "Accession": "11182" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RBFOX2", "Accession": "23543" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FCGR1B", "Accession": "2210" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "P2RY13", "Accession": "53829" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BTN3A3", "Accession": "10384" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLAU", "Accession": "5328" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRIP6", "Accession": "7205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ABCG1", "Accession": "9619" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ME2", "Accession": "4200" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FKBP1A", "Accession": "2280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AXL", "Accession": "558" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NR1H3", "Accession": "10062" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACP2", "Accession": "53" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LARP6", "Accession": "55323" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LIPG", "Accession": "9388" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYL9", "Accession": "10398" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GALNT2", "Accession": "2590" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BMP6", "Accession": "654" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DENND5A", "Accession": "23258" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SV2A", "Accession": "9900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF22", "Accession": "7570" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LIMK2", "Accession": "3985" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "C2", "Accession": "717" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DRAM1", "Accession": "55332" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CDH13", "Accession": "1012" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL8A1", "Accession": "1295" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYH9", "Accession": "4627" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CYLD", "Accession": "1540" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITGB3", "Accession": "3690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCNL1", "Accession": "57018" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NCKAP1L", "Accession": "3071" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADGRL4", "Accession": "64123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLT8D2", "Accession": "83468" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PAK2", "Accession": "5062" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BMX", "Accession": "660" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DOCK1", "Accession": "1793" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FCHSD2", "Accession": "9873" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRPF8", "Accession": "10594" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "lipoprotein particle receptor binding (GO:0070325)", "Accession": "GO:0070325" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "constipation", "Accession": "C0009806" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "dizziness", "Accession": "C0012833" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "infection", "Accession": "C0021311" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "hypersensitivity", "Accession": "C0020517" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "paraesthesia", "Accession": "C0030554" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "fatigue", "Accession": "C0015672" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "rash", "Accession": "C0015230" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "dyspnoea", "Accession": "C0013404" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "neuropathy peripheral", "Accession": "C0031117" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "focal adhesion (GO:0005925)", "Accession": "GO:0005925" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "caveola (GO:0005901)", "Accession": "GO:0005901" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "MACCS75", "Accession": "A!N$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS85", "Accession": "CN(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS91", "Accession": "QHAAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS93", "Accession": "QCH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS97", "Accession": "NAAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS98", "Accession": "QAAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS104", "Accession": "QHACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS108", "Accession": "CH3AAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS111", "Accession": "NACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS116", "Accession": "CH3AACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS118", "Accession": "ACH2CH2A > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS121", "Accession": "N HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS122", "Accession": "AN(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS125", "Accession": "AROMATIC RING > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS128", "Accession": "ACH2AAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS129", "Accession": "ACH2AACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS131", "Accession": "QH > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS132", "Accession": "OACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS137", "Accession": "HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS139", "Accession": "OH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS145", "Accession": "6M RING > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS147", "Accession": "ACH2CH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS148", "Accession": "AQ(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS150", "Accession": "A!A$A!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS152", "Accession": "OC(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS155", "Accession": "A!CH2!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS156", "Accession": "NA(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS157", "Accession": "C-O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS158", "Accession": "C-N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS159", "Accession": "O > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS160", "Accession": "CH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS161", "Accession": "N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS162", "Accession": "AROMATIC" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS163", "Accession": "6M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS164", "Accession": "O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS165", "Accession": "RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "regulation of cell migration (GO:0030334)", "Accession": "GO:0030334" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of cell proliferation (GO:0042127)", "Accession": "GO:0042127" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of epithelial cell proliferation (GO:0050680)", "Accession": "GO:0050680" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "extracellular matrix organization (GO:0030198)", "Accession": "GO:0030198" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of substrate adhesion-dependent cell spreading (GO:1900024)", "Accession": "GO:1900024" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of cell-substrate adhesion (GO:0010811)", "Accession": "GO:0010811" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "chylomicron remodeling (GO:0034371)", "Accession": "GO:0034371" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "triglyceride-rich lipoprotein particle remodeling (GO:0034370)", "Accession": "GO:0034370" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of substrate adhesion-dependent cell spreading (GO:1900026)", "Accession": "GO:1900026" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of transcription, DNA-templated (GO:0045892)", "Accession": "GO:0045892" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "epidermis development (GO:0008544)", "Accession": "GO:0008544" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "chylomicron assembly (GO:0034378)", "Accession": "GO:0034378" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of epithelial cell apoptotic process (GO:1904036)", "Accession": "GO:1904036" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of epithelial cell migration (GO:0010634)", "Accession": "GO:0010634" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "very-low-density lipoprotein particle (GO:0034361)", "Accession": "GO:0034361" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "Focal adhesion", "Accession": "map04510" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Regulation of actin cytoskeleton", "Accession": "map04810" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Aldosterone-regulated sodium reabsorption", "Accession": "map04960" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Bacterial invasion of epithelial cells", "Accession": "map05100" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down", "Association_type": "KEGG pathways" } ] }