{ "Entity": { "Name": "pt-630", "SMILES": "B(C1CCCN1C(=O)C(CCC(=O)O)N)(O)O", "Accession": "BRD-A73680854", "InChI_key": "DMTPQYQQHYOTQM-MLWJPKLSSA-N" }, "Associations": [ { "Term": [ { "Name": "PPAR signaling pathway", "Accession": "map03320" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Relaxin signaling pathway", "Accession": "map04926" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Folate biosynthesis", "Accession": "map00790" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Gap junction", "Accession": "map04540" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Fructose and mannose metabolism", "Accession": "map00051" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": ">= 4 H", "Accession": "PubChem0" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 8 H", "Accession": "PubChem1" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 16 H", "Accession": "PubChem2" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 B", "Accession": "PubChem6" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 C", "Accession": "PubChem9" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 4 C", "Accession": "PubChem10" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 8 C", "Accession": "PubChem11" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 N", "Accession": "PubChem14" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 N", "Accession": "PubChem15" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 O", "Accession": "PubChem18" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 O", "Accession": "PubChem19" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 4 O", "Accession": "PubChem20" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 any ring size 5", "Accession": "PubChem143" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic nitrogen-containing ring size 5", "Accession": "PubChem145" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic heteroatom-containing ring size 5", "Accession": "PubChem146" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "B-C", "Accession": "PubChem274" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "B-O", "Accession": "PubChem276" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-H", "Accession": "PubChem283" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C", "Accession": "PubChem284" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N", "Accession": "PubChem285" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-O", "Accession": "PubChem286" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-H", "Accession": "PubChem299" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-H", "Accession": "PubChem308" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)", "Accession": "PubChem332" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~H)(~N)", "Accession": "PubChem338" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~N)", "Accession": "PubChem340" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)", "Accession": "PubChem344" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)(~N)", "Accession": "PubChem345" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~N)", "Accession": "PubChem351" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~O)", "Accession": "PubChem352" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(~N)", "Accession": "PubChem365" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~O)(~O)", "Accession": "PubChem380" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)", "Accession": "PubChem390" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)(~C)", "Accession": "PubChem391" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~H)", "Accession": "PubChem393" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O(~C)(~H)", "Accession": "PubChem406" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=O", "Accession": "PubChem420" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-N)(=O)", "Accession": "PubChem439" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-O)(=O)", "Accession": "PubChem440" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(=O)", "Accession": "PubChem443" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-N)(=O)", "Accession": "PubChem451" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-O)(=O)", "Accession": "PubChem452" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-N-C-[#1]", "Accession": "PubChem528" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C", "Accession": "PubChem535" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-N", "Accession": "PubChem536" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-[#1]", "Accession": "PubChem540" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-N", "Accession": "PubChem569" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C", "Accession": "PubChem579" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-C-C", "Accession": "PubChem582" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-C-C", "Accession": "PubChem592" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-N-C", "Accession": "PubChem611" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-C-C", "Accession": "PubChem613" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-C-O-[#1]", "Accession": "PubChem617" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C", "Accession": "PubChem637" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-C-C-N-[#1]", "Accession": "PubChem643" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-N-C-C", "Accession": "PubChem645" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-N-C-[#1]", "Accession": "PubChem646" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C-N-C-C", "Accession": "PubChem656" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C", "Accession": "PubChem680" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-N", "Accession": "PubChem682" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-C-C-C", "Accession": "PubChem683" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C-C", "Accession": "PubChem684" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C-N", "Accession": "PubChem685" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C-N", "Accession": "PubChem691" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C-C-O", "Accession": "PubChem693" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C-C=O", "Accession": "PubChem694" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O=C-C-C-C-C-N", "Accession": "PubChem695" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "O-C-C-C-C-C-N-C", "Accession": "PubChem702" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "GADD45B", "Accession": "4616" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NTRK2", "Accession": "4915" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MARCKS", "Accession": "4082" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSMB", "Accession": "4477" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DDX42", "Accession": "11325" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LRIG1", "Accession": "26018" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPX1", "Accession": "2876" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GNG11", "Accession": "2791" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TFF1", "Accession": "7031" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LTF", "Accession": "4057" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "G0S2", "Accession": "50486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADM", "Accession": "133" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MYO5C", "Accession": "55930" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ID3", "Accession": "3399" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH2", "Accession": "217" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEFH", "Accession": "4744" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EGFR", "Accession": "1956" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KYNU", "Accession": "8942" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CA12", "Accession": "771" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CHPT1", "Accession": "56994" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ASS1", "Accession": "445" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CAV1", "Accession": "857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TSPAN8", "Accession": "7103" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EIF5A", "Accession": "1984" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GATM", "Accession": "2628" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EFEMP1", "Accession": "2202" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GAS1", "Accession": "2619" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC4A4", "Accession": "8671" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT7", "Accession": "3855" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SRGN", "Accession": "5552" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ASPH", "Accession": "444" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL5A1", "Accession": "1289" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LYPD1", "Accession": "116372" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DAPK1", "Accession": "1612" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FLRT2", "Accession": "23768" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "G3BP1", "Accession": "10146" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "YBX3", "Accession": "8531" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL4A5", "Accession": "1287" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB6", "Accession": "84617" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1B10", "Accession": "57016" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP4", "Accession": "3487" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH3A1", "Accession": "218" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BASP1", "Accession": "10409" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NQO1", "Accession": "1728" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC38A1", "Accession": "81539" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCAND1", "Accession": "51282" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPINK1", "Accession": "6690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPL27A", "Accession": "6157" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TNS3", "Accession": "64759" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HPGD", "Accession": "3248" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GNAI1", "Accession": "2770" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SEMA3C", "Accession": "10512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AK4", "Accession": "205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPS11", "Accession": "6205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC7A11", "Accession": "23657" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "H2AC6", "Accession": "8334" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TM4SF1", "Accession": "4071" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MID1IP1", "Accession": "58526" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANXA1", "Accession": "301" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MUC5AC", "Accession": "4586" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DUOX2", "Accession": "50506" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1B1", "Accession": "231" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSLN", "Accession": "10232" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BACE2", "Accession": "25825" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PFKFB3", "Accession": "5209" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PSAT1", "Accession": "29968" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOLR1", "Accession": "2348" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "WWP1", "Accession": "11059" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LPL", "Accession": "4023" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IL6", "Accession": "3569" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FABP4", "Accession": "2167" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IRS2", "Accession": "8660" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCN2", "Accession": "1490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CLGN", "Accession": "1047" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HDGFL3", "Accession": "50810" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC1A4", "Accession": "6509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "S100A6", "Accession": "6277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FABP5", "Accession": "2171" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C1", "Accession": "1645" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPARG", "Accession": "5468" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SIK1", "Accession": "150094" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL11A1", "Accession": "1301" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SMAD3", "Accession": "4088" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ME1", "Accession": "4199" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPRC5A", "Accession": "9052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C2", "Accession": "1646" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C3", "Accession": "8644" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "S100P", "Accession": "6286" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CTSZ", "Accession": "1522" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FA2H", "Accession": "79152" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TXN", "Accession": "7295" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PFKP", "Accession": "5214" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPL37A", "Accession": "6168" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPL38", "Accession": "6169" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TXNDC9", "Accession": "10190" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLIN1", "Accession": "5346" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LOX", "Accession": "4015" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGFR2", "Accession": "2263" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPX2", "Accession": "2877" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SGCE", "Accession": "8910" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MECOM", "Accession": "2122" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TWIST1", "Accession": "7291" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRRG1", "Accession": "5638" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIN1", "Accession": "5300" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RHOBTB3", "Accession": "22836" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A7", "Accession": "9194" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADIPOQ", "Accession": "9370" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VOPP1", "Accession": "81552" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STC2", "Accession": "8614" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BICC1", "Accession": "80114" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC14B", "Accession": "8555" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DHCR24", "Accession": "1718" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LACTB2", "Accession": "51110" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TIMM17B", "Accession": "10245" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "YWHAE", "Accession": "7531" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDZK1", "Accession": "5174" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KCNJ16", "Accession": "3773" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL5", "Accession": "6374" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCDH9", "Accession": "5101" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NID2", "Accession": "22795" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RCN1", "Accession": "5954" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GJA1", "Accession": "2697" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRKCA", "Accession": "5578" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GBE1", "Accession": "2632" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NME1", "Accession": "4830" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RHOV", "Accession": "171177" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM97", "Accession": "27346" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR3C1", "Accession": "2908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CAVIN1", "Accession": "284119" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ROBO1", "Accession": "6091" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLEKHA5", "Accession": "54477" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TCN1", "Accession": "6947" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SEC22B", "Accession": "9554" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KIZ", "Accession": "55857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "INHBB", "Accession": "3625" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NNMT", "Accession": "4837" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PKM", "Accession": "5315" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "F3", "Accession": "2152" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FPGS", "Accession": "2356" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STUB1", "Accession": "10273" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "B4GALT1", "Accession": "2683" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MRPS16", "Accession": "51021" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CENPE", "Accession": "1062" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZCCHC24", "Accession": "219654" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LUM", "Accession": "4060" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAP3K5", "Accession": "4217" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRAS", "Accession": "3845" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PITX1", "Accession": "5307" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TNIP1", "Accession": "10318" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTGES", "Accession": "9536" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NME4", "Accession": "4833" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR2F1", "Accession": "7025" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PEX11A", "Accession": "8800" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PON2", "Accession": "5445" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANXA5", "Accession": "308" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AHNAK", "Accession": "79026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC20", "Accession": "991" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBE2E1", "Accession": "7324" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC42EP4", "Accession": "23580" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIGB", "Accession": "9488" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTPRM", "Accession": "5797" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TM4SF4", "Accession": "7104" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GRWD1", "Accession": "83743" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SORD", "Accession": "6652" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANXA3", "Accession": "306" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYTL1", "Accession": "54360" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPAG16", "Accession": "79582" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PEBP1", "Accession": "5037" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STMN2", "Accession": "11075" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EIF4B", "Accession": "1975" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SRC", "Accession": "6714" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABCA1", "Accession": "19" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBE3C", "Accession": "9690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GYG2", "Accession": "8908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "WWC1", "Accession": "23286" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIP", "Accession": "5304" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACACB", "Accession": "32" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TIMP4", "Accession": "7079" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IFRD2", "Accession": "7866" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ATP6V0E1", "Accession": "8992" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IRS1", "Accession": "3667" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PSCA", "Accession": "8000" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RTN3", "Accession": "10313" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPP25", "Accession": "54913" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDXK", "Accession": "8566" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STK32B", "Accession": "55351" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM164", "Accession": "84187" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MRPS12", "Accession": "6183" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR1D2", "Accession": "9975" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBE3B", "Accession": "89910" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NUSAP1", "Accession": "51203" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FLNB", "Accession": "2317" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STXBP2", "Accession": "6813" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NOTCH2NLB", "Accession": "100996763" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NRIP3", "Accession": "56675" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SMAD1", "Accession": "4086" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JAK1", "Accession": "3716" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "OPTN", "Accession": "10133" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZEB2", "Accession": "9839" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JADE3", "Accession": "9767" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CIDEC", "Accession": "63924" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AGPAT2", "Accession": "10555" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A5", "Accession": "9121" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BRD3", "Accession": "8019" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAT2B", "Accession": "27430" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SIGMAR1", "Accession": "10280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RAB11FIP1", "Accession": "80223" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KLK5", "Accession": "25818" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GRIA2", "Accession": "2891" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLSCR3", "Accession": "57048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NYNRIN", "Accession": "57523" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LY6E", "Accession": "4061" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CDH1", "Accession": "999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "JUND", "Accession": "3727" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEL1L3", "Accession": "23231" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LEF1", "Accession": "51176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MS4A1", "Accession": "931" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFITM1", "Accession": "8519" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CEACAM5", "Accession": "1048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ENTPD1", "Accession": "953" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "A2M", "Accession": "2" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DLK1", "Accession": "8788" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TFF3", "Accession": "7033" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RGS5", "Accession": "8490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MTSS1", "Accession": "9788" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EPCAM", "Accession": "4072" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "XYLT1", "Accession": "64131" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FAR2", "Accession": "55711" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RAMP1", "Accession": "10267" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFI30", "Accession": "10437" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SYT1", "Accession": "6857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NRGN", "Accession": "4900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HOPX", "Accession": "84525" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPARC", "Accession": "6678" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLU", "Accession": "1191" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CMAHP", "Accession": "8418" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EPS8", "Accession": "2059" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITGB2", "Accession": "3689" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BEX1", "Accession": "55859" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "POSTN", "Accession": "10631" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACTG2", "Accession": "72" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MMP12", "Accession": "4321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "YME1L1", "Accession": "10730" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLUL", "Accession": "2752" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CEACAM1", "Accession": "634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGL", "Accession": "3535" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC24A3", "Accession": "57419" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MGP", "Accession": "4256" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ASCL1", "Accession": "429" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SFRP1", "Accession": "6422" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RARRES1", "Accession": "5918" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SULF1", "Accession": "23213" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "S100A14", "Accession": "57402" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SFTPC", "Accession": "6440" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTSH", "Accession": "1512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "STK26", "Accession": "51765" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NT5E", "Accession": "4907" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CEACAM6", "Accession": "4680" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGHM", "Accession": "3507" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCP110", "Accession": "9738" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MEF2C", "Accession": "4208" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CHMP4A", "Accession": "29082" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GCNT1", "Accession": "2650" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRKCB", "Accession": "5579" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ANK3", "Accession": "288" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FBXO11", "Accession": "80204" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BGN", "Accession": "633" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RBP1", "Accession": "5947" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPINK2", "Accession": "6691" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ANP32E", "Accession": "81611" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAF", "Accession": "4094" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCNMA1", "Accession": "3778" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM45A", "Accession": "55076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RUFY3", "Accession": "22902" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGHD", "Accession": "3495" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAMK2N1", "Accession": "55450" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SELENBP1", "Accession": "8991" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPTSSA", "Accession": "171546" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SORL1", "Accession": "6653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ABAT", "Accession": "18" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PF4", "Accession": "5196" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL13", "Accession": "10563" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RNASE6", "Accession": "6039" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITGB7", "Accession": "3695" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEC14L1", "Accession": "6397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCR2", "Accession": "729230" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NES", "Accession": "10763" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AREG", "Accession": "374" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRBC1", "Accession": "28639" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CYFIP2", "Accession": "26999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC6A14", "Accession": "11254" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PSMD2", "Accession": "5708" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LCK", "Accession": "3932" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "USP13", "Accession": "8975" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNC", "Accession": "3371" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CRABP1", "Accession": "1381" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGKC", "Accession": "3514" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KLF4", "Accession": "9314" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FCER1G", "Accession": "2207" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GULP1", "Accession": "51454" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD163", "Accession": "9332" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CRABP2", "Accession": "1382" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RUBCNL", "Accession": "80183" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DST", "Accession": "667" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GAS7", "Accession": "8522" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCNB1IP1", "Accession": "57820" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPON2", "Accession": "10417" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ENDOD1", "Accession": "23052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "INSM1", "Accession": "3642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFI6", "Accession": "2537" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH1A3", "Accession": "220" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLEC3B", "Accession": "7123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL14A1", "Accession": "7373" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LAP3", "Accession": "51056" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TARP", "Accession": "445347" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PMM2", "Accession": "5373" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP5", "Accession": "3488" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB2A", "Accession": "7280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HIC2", "Accession": "23119" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SELENOW", "Accession": "6415" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTNNB1", "Accession": "1499" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ISYNA1", "Accession": "51477" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGKV4-1", "Accession": "28908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV1-40", "Accession": "28825" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "POU2AF1", "Accession": "5450" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DCLK1", "Accession": "9201" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PNMA8A", "Accession": "55228" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV3-19", "Accession": "28797" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GUSBP11", "Accession": "91316" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PI4KA", "Accession": "5297" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLJ3", "Accession": "28831" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TCF25", "Accession": "22980" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MICALL1", "Accession": "85377" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MEG3", "Accession": "55384" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCNMB1", "Accession": "3779" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NID1", "Accession": "4811" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALOX5AP", "Accession": "241" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CORO1A", "Accession": "11151" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRSS8", "Accession": "5652" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM158", "Accession": "25907" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ARID1A", "Accession": "8289" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RUNX3", "Accession": "864" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLDN3", "Accession": "1365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AMIGO2", "Accession": "347902" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "JAM3", "Accession": "83700" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TUBA1A", "Accession": "7846" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "JCHAIN", "Accession": "3512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IDS", "Accession": "3423" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IL2RB", "Accession": "3560" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LSP1", "Accession": "4046" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "WDTC1", "Accession": "23038" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DDAH1", "Accession": "23576" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP6", "Accession": "1848" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL9A3", "Accession": "1299" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD14", "Accession": "929" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRDV3", "Accession": "28516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRD", "Accession": "6964" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HMGCR", "Accession": "3156" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FKBP11", "Accession": "51303" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FAM3C", "Accession": "10447" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL1", "Accession": "2919" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PPBP", "Accession": "5473" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "P2RX5", "Accession": "5026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP10D", "Accession": "57205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC12A2", "Accession": "6558" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAGED1", "Accession": "9500" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP3", "Accession": "3486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF586", "Accession": "54807" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GCH1", "Accession": "2643" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RABGAP1L", "Accession": "9910" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NPTX2", "Accession": "4885" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRKCH", "Accession": "5583" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TENT5C", "Accession": "54855" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALAS2", "Accession": "212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "APOBEC3G", "Accession": "60489" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLG1", "Accession": "2734" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLDC", "Accession": "2731" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CXADR", "Accession": "1525" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PADI2", "Accession": "11240" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RAB25", "Accession": "57111" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RAB40B", "Accession": "10966" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PDHX", "Accession": "8050" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LSM5", "Accession": "23658" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AIF1", "Accession": "199" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGKV1-5", "Accession": "28299" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZSCAN18", "Accession": "65982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HBB", "Accession": "3043" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DSTN", "Accession": "11034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FNBP1", "Accession": "23048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RAP1GAP2", "Accession": "23108" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD164", "Accession": "8763" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP4", "Accession": "1846" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ENPEP", "Accession": "2028" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CIDEB", "Accession": "27141" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PAPOLA", "Accession": "10914" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "QPRT", "Accession": "23475" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLIC4", "Accession": "25932" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GNA14", "Accession": "9630" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CDH6", "Accession": "1004" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD3D", "Accession": "915" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ICAM1", "Accession": "3383" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HERPUD1", "Accession": "9709" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADAM9", "Accession": "8754" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PELO", "Accession": "53918" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NCOA3", "Accession": "8202" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FZD7", "Accession": "8324" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GLO1", "Accession": "2739" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM176B", "Accession": "28959" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLA1A", "Accession": "51365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGEF40", "Accession": "55701" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM176A", "Accession": "55365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MZB1", "Accession": "51237" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLL3P", "Accession": "91353" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LTBP3", "Accession": "4054" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "VDR", "Accession": "7421" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV2-23", "Accession": "28813" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNFRSF17", "Accession": "608" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GSPT1", "Accession": "2935" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SRP72", "Accession": "6731" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD300A", "Accession": "11314" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SF3A1", "Accession": "10291" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NKG7", "Accession": "4818" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SULT1A1", "Accession": "6817" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SV2A", "Accession": "9900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADGRL1", "Accession": "22859" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TERF2IP", "Accession": "54386" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "XCL1", "Accession": "6375" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLCG2", "Accession": "5336" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF83", "Accession": "55769" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RALGAPA1", "Accession": "253959" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CALHM2", "Accession": "51063" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ARC", "Accession": "23237" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPATA2L", "Accession": "124044" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP8", "Accession": "1850" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ketosteroid monooxygenase activity (GO:0047086)", "Accession": "GO:0047086" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "aldo-keto reductase (NADP) activity (GO:0004033)", "Accession": "GO:0004033" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "alditol:NADP+ 1-oxidoreductase activity (GO:0004032)", "Accession": "GO:0004032" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (GO:0016655)", "Accession": "GO:0016655" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "alcohol dehydrogenase (NADP+) activity (GO:0008106)", "Accession": "GO:0008106" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "tinnitus", "Accession": "C0040264" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "hypersensitivity", "Accession": "C0020517" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "back pain", "Accession": "C0004604" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "anxiety", "Accession": "C0003467" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "fatigue", "Accession": "C0015672" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "hypertension", "Accession": "C0020538" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "confusional state", "Accession": "C0009676" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "MACCS18", "Accession": "GROUP IIIA (B...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS43", "Accession": "QHAQH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS44", "Accession": "OTHER" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS69", "Accession": "QQH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS75", "Accession": "A!N$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS79", "Accession": "NAAN" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS83", "Accession": "QAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS84", "Accession": "NH2" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS85", "Accession": "CN(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS90", "Accession": "QHAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS91", "Accession": "QHAAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS92", "Accession": "OC(N)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS95", "Accession": "NAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS96", "Accession": "5M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS100", "Accession": "ACH2N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS102", "Accession": "QO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS104", "Accession": "QHACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS110", "Accession": "NCO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS111", "Accession": "NACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS117", "Accession": "NAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS118", "Accession": "ACH2CH2A > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS121", "Accession": "N HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS122", "Accession": "AN(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS123", "Accession": "OCO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS124", "Accession": "QQ" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS128", "Accession": "ACH2AAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS129", "Accession": "ACH2AACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS130", "Accession": "QQ > 1 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS131", "Accession": "QH > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS132", "Accession": "OACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS136", "Accession": "O=A > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS137", "Accession": "HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS139", "Accession": "OH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS140", "Accession": "O > 3 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS142", "Accession": "N > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS146", "Accession": "O > 2" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS147", "Accession": "ACH2CH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS148", "Accession": "AQ(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS150", "Accession": "A!A$A!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS151", "Accession": "NH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS153", "Accession": "QCH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS154", "Accession": "C=O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS155", "Accession": "A!CH2!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS156", "Accession": "NA(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS157", "Accession": "C-O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS158", "Accession": "C-N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS159", "Accession": "O > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS161", "Accession": "N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS164", "Accession": "O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS165", "Accession": "RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "regulation of angiogenesis (GO:0045765)", "Accession": "GO:0045765" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cell proliferation (GO:0008285)", "Accession": "GO:0008285" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulated exocytosis (GO:0045055)", "Accession": "GO:0045055" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "extracellular matrix organization (GO:0030198)", "Accession": "GO:0030198" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of cell proliferation (GO:0042127)", "Accession": "GO:0042127" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "response to lipid (GO:0033993)", "Accession": "GO:0033993" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "response to calcium ion (GO:0051592)", "Accession": "GO:0051592" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "receptor-mediated endocytosis (GO:0006898)", "Accession": "GO:0006898" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "endocytosis (GO:0006897)", "Accession": "GO:0006897" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "complement activation, classical pathway (GO:0006958)", "Accession": "GO:0006958" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "humoral immune response mediated by circulating immunoglobulin (GO:0002455)", "Accession": "GO:0002455" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "Fc-gamma receptor signaling pathway (GO:0038094)", "Accession": "GO:0038094" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "Fc receptor mediated stimulatory signaling pathway (GO:0002431)", "Accession": "GO:0002431" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "chemokine-mediated signaling pathway (GO:0070098)", "Accession": "GO:0070098" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of leukocyte chemotaxis (GO:0002690)", "Accession": "GO:0002690" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "response to lipopolysaccharide (GO:0032496)", "Accession": "GO:0032496" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of leukocyte chemotaxis (GO:0002688)", "Accession": "GO:0002688" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of humoral immune response (GO:0002920)", "Accession": "GO:0002920" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of immune response (GO:0050776)", "Accession": "GO:0050776" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of chemotaxis (GO:0050921)", "Accession": "GO:0050921" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of leukocyte migration (GO:0002687)", "Accession": "GO:0002687" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of epithelial cell proliferation (GO:0050680)", "Accession": "GO:0050680" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of anatomical structure morphogenesis (GO:0022603)", "Accession": "GO:0022603" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of neutrophil chemotaxis (GO:0090022)", "Accession": "GO:0090022" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of smooth muscle cell migration (GO:0014912)", "Accession": "GO:0014912" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "phagocytosis (GO:0006909)", "Accession": "GO:0006909" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cellular response to organic substance (GO:0071310)", "Accession": "GO:0071310" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of lipid metabolic process (GO:0019216)", "Accession": "GO:0019216" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of primary metabolic process (GO:0080090)", "Accession": "GO:0080090" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cellular response to peptide hormone stimulus (GO:0071375)", "Accession": "GO:0071375" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cellular response to hormone stimulus (GO:0032870)", "Accession": "GO:0032870" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "prostaglandin metabolic process (GO:0006693)", "Accession": "GO:0006693" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "doxorubicin metabolic process (GO:0044598)", "Accession": "GO:0044598" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "prostanoid metabolic process (GO:0006692)", "Accession": "GO:0006692" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "aminoglycoside antibiotic metabolic process (GO:0030647)", "Accession": "GO:0030647" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "daunorubicin metabolic process (GO:0044597)", "Accession": "GO:0044597" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "quinone metabolic process (GO:1901661)", "Accession": "GO:1901661" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "glycoside metabolic process (GO:0016137)", "Accession": "GO:0016137" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cell differentiation (GO:0045596)", "Accession": "GO:0045596" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "progesterone metabolic process (GO:0042448)", "Accession": "GO:0042448" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "focal adhesion (GO:0005925)", "Accession": "GO:0005925" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" } ] }