{ "Entity": { "Name": "2-aminopurine", "SMILES": "C1=C2C(=NC(=N1)N)N=CN2", "Accession": "BRD-K35128472", "InChI_key": "MWBWWFOAEOYUST-UHFFFAOYSA-N" }, "Associations": [ { "Term": [ { "Name": "Focal adhesion", "Accession": "map04510" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "ECM-receptor interaction", "Accession": "map04512" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Cell cycle", "Accession": "map04110" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Complement and coagulation cascades", "Accession": "map04610" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "PI3K-Akt signaling pathway", "Accession": "map04151" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "p53 signaling pathway", "Accession": "map04115" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "TGF-beta signaling pathway", "Accession": "map04350" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": "Adherens junction", "Accession": "map04520" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up", "Association_type": "KEGG pathways" }, { "Term": [ { "Name": ">= 4 H", "Accession": "PubChem0" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 C", "Accession": "PubChem9" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 4 C", "Accession": "PubChem10" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 N", "Accession": "PubChem14" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 N", "Accession": "PubChem15" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 4 N", "Accession": "PubChem16" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 any ring size 5", "Accession": "PubChem143" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic nitrogen-containing ring size 5", "Accession": "PubChem145" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic heteroatom-containing ring size 5", "Accession": "PubChem146" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 any ring size 6", "Accession": "PubChem178" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic nitrogen-containing ring size 6", "Accession": "PubChem180" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic heteroatom-containing ring size 6", "Accession": "PubChem181" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 any ring size 9", "Accession": "PubChem241" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic nitrogen-containing ring size 9", "Accession": "PubChem243" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 saturated or aromatic heteroatom-containing ring size 9", "Accession": "PubChem244" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 aromatic ring", "Accession": "PubChem255" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 1 hetero-aromatic ring", "Accession": "PubChem256" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 aromatic rings", "Accession": "PubChem257" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 2 hetero-aromatic rings", "Accession": "PubChem258" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 3 aromatic rings", "Accession": "PubChem259" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": ">= 3 hetero-aromatic rings", "Accession": "PubChem260" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-H", "Accession": "PubChem283" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C", "Accession": "PubChem284" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N", "Accession": "PubChem285" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-H", "Accession": "PubChem299" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)", "Accession": "PubChem332" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~C)(~N)", "Accession": "PubChem340" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)", "Accession": "PubChem344" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~H)(~N)", "Accession": "PubChem345" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(~N)", "Accession": "PubChem351" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:C)", "Accession": "PubChem355" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:C)(:N)", "Accession": "PubChem357" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:N)", "Accession": "PubChem358" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~C)(:N)(:N)", "Accession": "PubChem359" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(~N)", "Accession": "PubChem365" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(:C)", "Accession": "PubChem370" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(:C)(:N)", "Accession": "PubChem372" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~H)(:N)", "Accession": "PubChem373" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~N)(~N)", "Accession": "PubChem375" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~N)(:C)", "Accession": "PubChem376" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~N)(:C)(:C)", "Accession": "PubChem377" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~N)(:C)(:N)", "Accession": "PubChem378" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(~N)(:N)", "Accession": "PubChem379" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:C)(:C)", "Accession": "PubChem384" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:C)(:C)(:N)", "Accession": "PubChem386" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:C)(:N)", "Accession": "PubChem387" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:C)(:N)(:N)", "Accession": "PubChem388" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(:N)(:N)", "Accession": "PubChem389" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)", "Accession": "PubChem390" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~C)(~H)", "Accession": "PubChem392" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(~H)", "Accession": "PubChem393" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~C)(:C)", "Accession": "PubChem396" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~H)(:C)", "Accession": "PubChem399" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(~H)(:C)(:C)", "Accession": "PubChem400" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(:C)(:C)", "Accession": "PubChem403" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=C", "Accession": "PubChem416" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C=N", "Accession": "PubChem418" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-C)(=N)", "Accession": "PubChem431" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-H)(=N)", "Accession": "PubChem435" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-N)(=C)", "Accession": "PubChem437" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(-N)(=N)", "Accession": "PubChem438" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(=C)", "Accession": "PubChem441" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-C)(=N)", "Accession": "PubChem442" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-H)(-N)(=C)", "Accession": "PubChem445" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-H)(=C)", "Accession": "PubChem446" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-H)(=N)", "Accession": "PubChem447" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-N)(=C)", "Accession": "PubChem449" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C(-N)(=N)", "Accession": "PubChem450" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N(-C)(=C)", "Accession": "PubChem453" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C=C", "Accession": "PubChem464" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:N:C-C", "Accession": "PubChem472" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:N-C:C", "Accession": "PubChem482" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:N:C", "Accession": "PubChem484" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N:C:C:N", "Accession": "PubChem485" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C=N-C", "Accession": "PubChem487" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C=N-[#1]", "Accession": "PubChem488" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N:C-[#1]", "Accession": "PubChem491" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C:C", "Accession": "PubChem495" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C:N", "Accession": "PubChem499" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C=C-[#1]", "Accession": "PubChem502" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N:C:N-C", "Accession": "PubChem504" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C:N:C", "Accession": "PubChem506" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-N-C", "Accession": "PubChem519" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:N-C-[#1]", "Accession": "PubChem521" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N:C:C-C", "Accession": "PubChem523" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C:C:N-[#1]", "Accession": "PubChem527" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-N-C-[#1]", "Accession": "PubChem528" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N:C-C:C", "Accession": "PubChem530" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-C-C", "Accession": "PubChem538" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-C-[#1]", "Accession": "PubChem539" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-[#1]", "Accession": "PubChem540" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C-C", "Accession": "PubChem545" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C-[#1]", "Accession": "PubChem546" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C-N", "Accession": "PubChem547" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C:C", "Accession": "PubChem549" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-C=C", "Accession": "PubChem555" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-N-C", "Accession": "PubChem560" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-N", "Accession": "PubChem569" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N:C:N:C", "Accession": "PubChem572" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-C:C-[#1]", "Accession": "PubChem576" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-C:C-N-C", "Accession": "PubChem585" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-C-N", "Accession": "PubChem593" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N=C-N-C-C", "Accession": "PubChem596" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C:C-N", "Accession": "PubChem601" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-C-N-C", "Accession": "PubChem611" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-C-C", "Accession": "PubChem613" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C:C:C:N", "Accession": "PubChem621" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-C:C", "Accession": "PubChem628" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C-N-C", "Accession": "PubChem636" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "[#1]-C-C-N-[#1]", "Accession": "PubChem643" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-N-C-C", "Accession": "PubChem654" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "C-N-C:C-C", "Accession": "PubChem657" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "N-C-N-C:C", "Accession": "PubChem674" } ], "Filename": "PubChem_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "CPM", "Accession": "1368" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ITPRID2", "Accession": "6744" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GADD45B", "Accession": "4616" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FCGBP", "Accession": "8857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CNN3", "Accession": "1266" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NTS", "Accession": "4922" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DTL", "Accession": "51514" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SEC62", "Accession": "7095" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYP26B1", "Accession": "56603" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM45A", "Accession": "55076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HOXB6", "Accession": "3216" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HOXB7", "Accession": "3217" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL4A3", "Accession": "1285" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALML5", "Accession": "51806" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TLE1", "Accession": "7088" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPARC", "Accession": "6678" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COCH", "Accession": "1690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VCAN", "Accession": "1462" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADM", "Accession": "133" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ID3", "Accession": "3399" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRKACB", "Accession": "5567" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGLL1", "Accession": "3543" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SORBS3", "Accession": "10174" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MID1", "Accession": "4281" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "OSR2", "Accession": "116039" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CREB3L2", "Accession": "64764" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AHNAK2", "Accession": "113146" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HLA-DQA1", "Accession": "3117" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGAP29", "Accession": "9411" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CPS1", "Accession": "1373" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGLJ3", "Accession": "28831" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRIM2", "Accession": "23321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT7", "Accession": "3855" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ME2", "Accession": "4200" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACAT1", "Accession": "38" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VSIG4", "Accession": "11326" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TCEAL2", "Accession": "140597" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DEGS1", "Accession": "8560" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDE4B", "Accession": "5142" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RRM2", "Accession": "6241" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MKI67", "Accession": "4288" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NFIB", "Accession": "4781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PON3", "Accession": "5446" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GSDME", "Accession": "1687" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HPSE", "Accession": "10855" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCND2", "Accession": "894" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BCHE", "Accession": "590" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "YBX3", "Accession": "8531" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TGFB1I1", "Accession": "7041" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGHM", "Accession": "3507" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBB6", "Accession": "84617" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGL", "Accession": "3535" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JCHAIN", "Accession": "3512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CREM", "Accession": "1390" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NID1", "Accession": "4811" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GUSBP11", "Accession": "91316" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GALC", "Accession": "2581" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CXADR", "Accession": "1525" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SAT1", "Accession": "6303" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH1A3", "Accession": "220" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SERPINA3", "Accession": "12" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRABP2", "Accession": "1382" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADGRG6", "Accession": "57211" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGDIB", "Accession": "397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AQP3", "Accession": "360" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGHD", "Accession": "3495" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV2-23", "Accession": "28813" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NAMPT", "Accession": "10135" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGKV1-5", "Accession": "28299" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGKV3-20", "Accession": "28912" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SKAP2", "Accession": "8935" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LIMCH1", "Accession": "22998" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HOPX", "Accession": "84525" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD99", "Accession": "4267" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV3-19", "Accession": "28797" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJC12", "Accession": "56521" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANXA1", "Accession": "301" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ERBB2", "Accession": "2064" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CLEC2B", "Accession": "9976" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAFF", "Accession": "23764" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGG", "Accession": "2266" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MTUS1", "Accession": "57509" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VIM", "Accession": "7431" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "THBS2", "Accession": "7058" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP1", "Accession": "3484" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP5", "Accession": "3488" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRAME", "Accession": "23532" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TFPI", "Accession": "7035" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1B1", "Accession": "231" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSLN", "Accession": "10232" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RARRES1", "Accession": "5918" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD55", "Accession": "1604" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GABARAPL1", "Accession": "23710" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PFKFB3", "Accession": "5209" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTP4A1", "Accession": "7803" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KLK5", "Accession": "25818" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HMOX1", "Accession": "3162" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT14", "Accession": "3861" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IRS2", "Accession": "8660" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCN2", "Accession": "1490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCN1", "Accession": "3491" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TSPAN13", "Accession": "27075" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DHRS3", "Accession": "9249" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HTATIP2", "Accession": "10553" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IL18", "Accession": "3606" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRIP6", "Accession": "7205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CLTB", "Accession": "1212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SIK1", "Accession": "150094" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EPAS1", "Accession": "2034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP3", "Accession": "3486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT17", "Accession": "3872" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL11A1", "Accession": "1301" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SMAD3", "Accession": "4088" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STOM", "Accession": "2040" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ME1", "Accession": "4199" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPRC5A", "Accession": "9052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UGDH", "Accession": "7358" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "S100P", "Accession": "6286" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ID1", "Accession": "3397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HSP90AA1", "Accession": "3320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSN", "Accession": "4478" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR4A2", "Accession": "4929" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TUBA4A", "Accession": "7277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TSPAN12", "Accession": "23554" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDKN2C", "Accession": "1031" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CTSK", "Accession": "1513" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GABBR2", "Accession": "9568" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCNN1A", "Accession": "6337" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CEACAM6", "Accession": "4680" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EFNA1", "Accession": "1942" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL5A2", "Accession": "1290" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGB", "Accession": "2244" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AEBP1", "Accession": "165" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MXRA5", "Accession": "25878" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PAM", "Accession": "5066" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LITAF", "Accession": "9516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FARP1", "Accession": "10160" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GPSM2", "Accession": "29899" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HADHA", "Accession": "3030" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLS3", "Accession": "5358" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RHOBTB3", "Accession": "22836" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MYO6", "Accession": "4646" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MDFIC", "Accession": "29969" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGLL3P", "Accession": "91353" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC2A3", "Accession": "6515" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CP", "Accession": "1356" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SULF1", "Accession": "23213" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KCNJ16", "Accession": "3773" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PHYH", "Accession": "5264" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLIN2", "Accession": "123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LAMB1", "Accession": "3912" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GJA1", "Accession": "2697" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACTN1", "Accession": "87" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ECM1", "Accession": "1893" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MMP7", "Accession": "4316" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BGN", "Accession": "633" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD9", "Accession": "928" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJB2", "Accession": "3300" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR3C1", "Accession": "2908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COPA", "Accession": "1314" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PSIP1", "Accession": "11168" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RFC2", "Accession": "5982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJB9", "Accession": "4189" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "XBP1", "Accession": "7494" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LXN", "Accession": "56925" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NNMT", "Accession": "4837" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "F3", "Accession": "2152" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LMO3", "Accession": "55885" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACAA2", "Accession": "10449" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TGIF1", "Accession": "7050" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ETV1", "Accession": "2115" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CTSV", "Accession": "1515" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "OXA1L", "Accession": "5018" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCNB2", "Accession": "9133" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LEF1", "Accession": "51176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DCN", "Accession": "1634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HAL", "Accession": "3034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FN1", "Accession": "2335" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LUM", "Accession": "4060" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TPD52L1", "Accession": "7164" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDK1", "Accession": "983" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PALLD", "Accession": "23022" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FABP7", "Accession": "2173" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACTB", "Accession": "60" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTTG1", "Accession": "9232" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GLRX", "Accession": "2745" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RCAN1", "Accession": "1827" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "INHBA", "Accession": "3624" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL1A1", "Accession": "1277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COL10A1", "Accession": "1300" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALD1", "Accession": "800" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NT5E", "Accession": "4907" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAN1A1", "Accession": "4121" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ISG20", "Accession": "3669" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MFAP3L", "Accession": "9848" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BTG3", "Accession": "10950" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GRIA2", "Accession": "2891" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR2F1", "Accession": "7025" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANOS1", "Accession": "3730" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PON2", "Accession": "5445" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC20", "Accession": "991" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NMU", "Accession": "10874" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FAR2", "Accession": "55711" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MMP11", "Accession": "4320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABLIM1", "Accession": "3983" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDC25B", "Accession": "994" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALCAM", "Accession": "214" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NBL1", "Accession": "4681" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEK2", "Accession": "4751" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NRGN", "Accession": "4900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADAT1", "Accession": "23536" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FLRT3", "Accession": "23767" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IQGAP1", "Accession": "8826" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRH", "Accession": "7200" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HMGB1", "Accession": "3146" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDGFC", "Accession": "56034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "POSTN", "Accession": "10631" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LHX2", "Accession": "9355" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VCL", "Accession": "7414" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCLAF", "Accession": "9768" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EDNRA", "Accession": "1909" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTMA", "Accession": "5757" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MELK", "Accession": "9833" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LDHB", "Accession": "3945" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYBRD1", "Accession": "79901" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BLVRA", "Accession": "644" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LGALS1", "Accession": "3956" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC12A8", "Accession": "84561" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBE2C", "Accession": "11065" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RAB31", "Accession": "11031" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ITGB5", "Accession": "3693" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACOT9", "Accession": "23597" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ST7", "Accession": "7982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KIF20A", "Accession": "10112" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MTF2", "Accession": "22823" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IFIT3", "Accession": "3437" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "C5", "Accession": "727" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLCXD1", "Accession": "55344" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ITGB4", "Accession": "3691" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GOLGA4", "Accession": "2803" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NUSAP1", "Accession": "51203" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPN2", "Accession": "6185" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TOP2A", "Accession": "7153" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TBXA2R", "Accession": "6915" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC11A2", "Accession": "4891" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PRC1", "Accession": "9055" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBXN4", "Accession": "23190" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOXM1", "Accession": "2305" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KIF18B", "Accession": "146909" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CSGALNACT2", "Accession": "55454" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDE8B", "Accession": "8622" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HMMR", "Accession": "3161" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBB", "Accession": "7314" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TK1", "Accession": "7083" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TYMS", "Accession": "7298" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HAMP", "Accession": "57817" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CKS1B", "Accession": "1163" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SNRPD3", "Accession": "6634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "JOSD1", "Accession": "9929" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CDS2", "Accession": "8760" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NDC80", "Accession": "10403" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ATP1B3", "Accession": "483" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ASPM", "Accession": "259266" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "YWHAH", "Accession": "7533" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FAM114A1", "Accession": "92689" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALU", "Accession": "813" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KIF2C", "Accession": "11004" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CAPZA2", "Accession": "830" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LPGAT1", "Accession": "9926" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CEP55", "Accession": "55165" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GTSE1", "Accession": "51512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIEZO1", "Accession": "9780" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GNG5", "Accession": "2787" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DLGAP5", "Accession": "9787" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BIRC5", "Accession": "332" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RTCA", "Accession": "8634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FANCI", "Accession": "55215" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCARB2", "Accession": "950" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "YWHAE", "Accession": "7531" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MEIS1", "Accession": "4211" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP2", "Accession": "3485" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZBTB18", "Accession": "10472" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SRD5A1", "Accession": "6715" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAB21L2", "Accession": "10586" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACTN2", "Accession": "88" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MARCHF6", "Accession": "10299" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GUCY1A1", "Accession": "2982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LYZ", "Accession": "4069" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ENPP2", "Accession": "5168" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "STC1", "Accession": "6781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTPRN2", "Accession": "5799" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYBPC1", "Accession": "4604" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FABP5", "Accession": "2171" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C1", "Accession": "1645" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C2", "Accession": "1646" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MPZL2", "Accession": "10205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DICER1", "Accession": "23405" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DLK1", "Accession": "8788" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SELENOP", "Accession": "6414" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TFF3", "Accession": "7033" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SERPINA1", "Accession": "5265" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SYNJ2", "Accession": "8871" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CA12", "Accession": "771" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BHLHE41", "Accession": "79365" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYC", "Accession": "4609" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCTD12", "Accession": "115207" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRR7", "Accession": "80758" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLEC", "Accession": "5339" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MECOM", "Accession": "2122" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RRS1", "Accession": "23212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "VCAM1", "Accession": "7412" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLU", "Accession": "1191" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SOX4", "Accession": "6659" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSRP1", "Accession": "1465" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MMP12", "Accession": "4321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNS1", "Accession": "7145" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FABP4", "Accession": "2167" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RRAD", "Accession": "6236" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALDH1A1", "Accession": "216" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SERTAD2", "Accession": "9792" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYB", "Accession": "4602" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AMACR", "Accession": "23600" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HNMT", "Accession": "3176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PENK", "Accession": "5179" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC45A2", "Accession": "51151" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPINK2", "Accession": "6691" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SETBP1", "Accession": "26040" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAN2A1", "Accession": "4124" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KRT13", "Accession": "3860" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "INSIG1", "Accession": "3638" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACLY", "Accession": "47" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC37A4", "Accession": "2542" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DPP4", "Accession": "1803" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CES1", "Accession": "1066" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "B4GAT1", "Accession": "11041" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ALOX5", "Accession": "240" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNS3", "Accession": "64759" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCL20", "Accession": "6364" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC5A6", "Accession": "8884" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PDZK1", "Accession": "5174" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PNN", "Accession": "5411" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "C2CD5", "Accession": "9847" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGF1R", "Accession": "3480" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBC1D4", "Accession": "9882" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNC", "Accession": "3371" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CPA3", "Accession": "1359" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KLF4", "Accession": "9314" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD36", "Accession": "948" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GOLGA8A", "Accession": "23015" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBC1D9", "Accession": "23158" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "S100A8", "Accession": "6279" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AK4", "Accession": "205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SINHCAF", "Accession": "58516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP2A2", "Accession": "488" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CADM1", "Accession": "23705" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC27A3", "Accession": "11000" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRG2", "Accession": "5553" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "INSM1", "Accession": "3642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLEC3B", "Accession": "7123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL1A1", "Accession": "1277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TARP", "Accession": "445347" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "G3BP2", "Accession": "9908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AKAP1", "Accession": "8165" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "S100A9", "Accession": "6280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMX1", "Accession": "81542" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DOCK10", "Accession": "55619" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSTA", "Accession": "1475" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ABCC4", "Accession": "10257" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CX3CR1", "Accession": "1524" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "POLR2I", "Accession": "5438" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "OLFM1", "Accession": "10439" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBCB", "Accession": "1155" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCD", "Accession": "6319" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ANPEP", "Accession": "290" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FHL1", "Accession": "2273" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP2", "Accession": "1844" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FGFR1", "Accession": "2260" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PHLDA2", "Accession": "7262" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NAV3", "Accession": "89795" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NKX3-1", "Accession": "4824" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NET1", "Accession": "10276" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL6A1", "Accession": "1291" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSF2RB", "Accession": "1439" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CUX2", "Accession": "23316" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GZMB", "Accession": "3002" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LDLR", "Accession": "3949" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LEPR", "Accession": "3953" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AUTS2", "Accession": "26053" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RNASE1", "Accession": "6035" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF423", "Accession": "23090" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TXN", "Accession": "7295" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FUCA1", "Accession": "2517" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TUSC3", "Accession": "7991" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLC", "Accession": "1178" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PVALB", "Accession": "5816" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "G0S2", "Accession": "50486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LAMA3", "Accession": "3909" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BMI1", "Accession": "648" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TAF10", "Accession": "6881" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TSPAN1", "Accession": "10103" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAPRIN1", "Accession": "4076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMPRSS11E", "Accession": "28983" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTSG", "Accession": "1511" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CHST2", "Accession": "9435" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "OGT", "Accession": "8473" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM87A", "Accession": "25963" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP7B", "Accession": "540" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NDUFA4L2", "Accession": "56901" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PAFAH1B3", "Accession": "5050" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TTR", "Accession": "7276" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRODH", "Accession": "5625" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HIPK2", "Accession": "28996" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PURA", "Accession": "5813" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HPCAL1", "Accession": "3241" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNNC2", "Accession": "7125" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "UBE2G1", "Accession": "7326" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRIM44", "Accession": "54765" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPAG7", "Accession": "9552" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GATA2", "Accession": "2624" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GALNT2", "Accession": "2590" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEMA4C", "Accession": "54910" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FAM117A", "Accession": "81558" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZBED5", "Accession": "58486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FOXO3", "Accession": "2309" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAP1A", "Accession": "4130" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "POLB", "Accession": "5423" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTER", "Accession": "9317" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ICAM3", "Accession": "3385" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZDHHC13", "Accession": "54503" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "agitation", "Accession": "C0085631" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "muscle spasms", "Accession": "C0037763" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "oedema", "Accession": "C0013604" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "nausea", "Accession": "C0027497" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "secretory granule lumen (GO:0034774)", "Accession": "GO:0034774" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "MACCS25", "Accession": "NC(N)N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS38", "Accession": "NC(C)N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS65", "Accession": "C%N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS77", "Accession": "NAN" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS79", "Accession": "NAAN" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS80", "Accession": "NAAAN" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS83", "Accession": "QAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS84", "Accession": "NH2" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS96", "Accession": "5M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS98", "Accession": "QAAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS101", "Accession": "8M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS105", "Accession": "A$A($A)$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS106", "Accession": "QA(Q)Q" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS120", "Accession": "HETEROCYCLIC ATOM > 1 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS121", "Accession": "N HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS125", "Accession": "AROMATIC RING > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS131", "Accession": "QH > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS133", "Accession": "A$A!N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS135", "Accession": "Nnot%A%A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS137", "Accession": "HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS142", "Accession": "N > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS151", "Accession": "NH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS156", "Accession": "NA(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS158", "Accession": "C-N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS161", "Accession": "N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS162", "Accession": "AROMATIC" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS163", "Accession": "6M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS165", "Accession": "RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "platelet degranulation (GO:0002576)", "Accession": "GO:0002576" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulated exocytosis (GO:0045055)", "Accession": "GO:0045055" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "extracellular matrix organization (GO:0030198)", "Accession": "GO:0030198" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of cell proliferation (GO:0008284)", "Accession": "GO:0008284" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "sulfur compound catabolic process (GO:0044273)", "Accession": "GO:0044273" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cell-matrix adhesion (GO:0007160)", "Accession": "GO:0007160" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "G2/M transition of mitotic cell cycle (GO:0000086)", "Accession": "GO:0000086" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cell cycle G2/M phase transition (GO:0044839)", "Accession": "GO:0044839" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "mitotic cell cycle phase transition (GO:0044772)", "Accession": "GO:0044772" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "platelet alpha granule (GO:0031091)", "Accession": "GO:0031091" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "focal adhesion (GO:0005925)", "Accession": "GO:0005925" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "endoplasmic reticulum lumen (GO:0005788)", "Accession": "GO:0005788" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "lysosomal lumen (GO:0043202)", "Accession": "GO:0043202" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "polymeric cytoskeletal fiber (GO:0099513)", "Accession": "GO:0099513" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" } ] }