{ "Entity": { "Name": "levcromakalim", "SMILES": "CC1(C(C(C2=C(O1)C=CC(=C2)C#N)N3CCCC3=O)O)C", "Accession": "BRD-K24526313", "InChI_key": "TVZCRIROJQEVOT-CABCVRRESA-N" }, "Associations": [ { "Term": [ { "Name": "exopeptidase activity (GO:0008238)", "Accession": "GO:0008238" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "peptidase activity, acting on L-amino acid peptides (GO:0070011)", "Accession": "GO:0070011" } ], "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "CIAPIN1", "Accession": "57019" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MSMB", "Accession": "4477" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SOD2", "Accession": "6648" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL1", "Accession": "2919" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APOD", "Accession": "347" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM45A", "Accession": "55076" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCL19", "Accession": "6363" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RHOB", "Accession": "388" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR2F2", "Accession": "7026" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TFF1", "Accession": "7031" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SYNGR3", "Accession": "9143" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SOX9", "Accession": "6662" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEFH", "Accession": "4744" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NKX3-1", "Accession": "4824" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT15", "Accession": "3866" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRISP3", "Accession": "10321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GSTA1", "Accession": "2938" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGAP29", "Accession": "9411" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GATA6", "Accession": "2627" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CPS1", "Accession": "1373" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOSB", "Accession": "2354" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT7", "Accession": "3855" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SRGN", "Accession": "5552" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYP1B1", "Accession": "1545" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ALOX5AP", "Accession": "241" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDE4B", "Accession": "5142" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMPRSS3", "Accession": "64699" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HSPB8", "Accession": "26353" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NFIB", "Accession": "4781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GNLY", "Accession": "10578" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "H2AZ2", "Accession": "94239" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCND2", "Accession": "894" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCL4", "Accession": "6351" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CCL5", "Accession": "6352" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NKG7", "Accession": "4818" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGHM", "Accession": "3507" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IGL", "Accession": "3535" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PEG10", "Accession": "23089" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLXNC1", "Accession": "10154" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GABRP", "Accession": "2568" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABL1", "Accession": "25" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IFI44L", "Accession": "10964" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TGFBR3", "Accession": "7049" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMX4", "Accession": "56255" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KLRK1", "Accession": "22914" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GATA3", "Accession": "2625" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CTSW", "Accession": "1521" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LIMCH1", "Accession": "22998" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GNAI1", "Accession": "2770" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMSB15A", "Accession": "11013" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKAP7", "Accession": "9465" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGG", "Accession": "2266" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STAR", "Accession": "6770" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KAZN", "Accession": "23254" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARG2", "Accession": "384" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AKAP12", "Accession": "9590" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IFI16", "Accession": "3428" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "VCAM1", "Accession": "7412" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDE10A", "Accession": "10846" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "F2RL1", "Accession": "2150" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CD55", "Accession": "1604" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PROM1", "Accession": "8842" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HEPH", "Accession": "9843" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "H2BC12", "Accession": "85236" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KRT14", "Accession": "3861" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPOCK1", "Accession": "6695" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IKZF1", "Accession": "10320" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP1", "Accession": "1843" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "IRS2", "Accession": "8660" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "OLFM1", "Accession": "10439" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BEX1", "Accession": "55859" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TSPAN13", "Accession": "27075" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BAG3", "Accession": "9531" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "S100P", "Accession": "6286" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TCF4", "Accession": "6925" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PID1", "Accession": "55022" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "XIST", "Accession": "7503" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AGTR1", "Accession": "185" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EFNA1", "Accession": "1942" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRPM4", "Accession": "54795" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ELF3", "Accession": "1999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NAV2", "Accession": "89797" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NMT2", "Accession": "9397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LITAF", "Accession": "9516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEBL", "Accession": "10529" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ORM1", "Accession": "5004" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RFC5", "Accession": "5985" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABCA8", "Accession": "10351" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AUTS2", "Accession": "26053" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STC2", "Accession": "8614" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FCGR3B", "Accession": "2215" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ABAT", "Accession": "18" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LMCD1", "Accession": "29995" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PCSK1", "Accession": "5122" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LAMB1", "Accession": "3912" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NID2", "Accession": "22795" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTPRK", "Accession": "5796" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TLE4", "Accession": "7091" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NR3C1", "Accession": "2908" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NFATC3", "Accession": "4775" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MOCOS", "Accession": "55034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TCF7L2", "Accession": "6934" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAPKAPK2", "Accession": "9261" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZFP36L2", "Accession": "678" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDZD2", "Accession": "23037" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RTN1", "Accession": "6252" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SUB1", "Accession": "10923" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ETV1", "Accession": "2115" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GZMK", "Accession": "3003" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RRP12", "Accession": "23223" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYP4B1", "Accession": "1580" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NAP1L1", "Accession": "4673" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "USP6NL", "Accession": "9712" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DCN", "Accession": "1634" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RNASE3", "Accession": "6037" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GZMA", "Accession": "3001" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PALLD", "Accession": "23022" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BPIFA1", "Accession": "51297" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SPRED2", "Accession": "200734" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ENC1", "Accession": "8507" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "COBL", "Accession": "23242" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLOD2", "Accession": "5352" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRD", "Accession": "6964" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RNASE4", "Accession": "6038" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPM1H", "Accession": "57460" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GOLM1", "Accession": "51280" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RUNX3", "Accession": "864" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SH3BP4", "Accession": "23677" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PTGES", "Accession": "9536" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ATP2C1", "Accession": "27032" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NAP1L3", "Accession": "4675" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CALD1", "Accession": "800" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EIF2AK3", "Accession": "9451" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MAN1A1", "Accession": "4121" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM47", "Accession": "83604" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ZBTB16", "Accession": "7704" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BLNK", "Accession": "29760" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ISG15", "Accession": "9636" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PDGFRL", "Accession": "5157" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ACAT2", "Accession": "39" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TACC2", "Accession": "10579" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TRDV3", "Accession": "28516" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MTSS1", "Accession": "9788" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PIH1D1", "Accession": "55011" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DOCK4", "Accession": "9732" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEK2", "Accession": "4751" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "TEX10", "Accession": "54881" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "OPN3", "Accession": "23596" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SCGB2A2", "Accession": "4250" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CYCS", "Accession": "54205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CGA", "Accession": "1081" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ETV5", "Accession": "2119" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RGS4", "Accession": "5999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "LEPR", "Accession": "3953" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DMD", "Accession": "1756" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "APBB2", "Accession": "323" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BCR", "Accession": "613" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PLCB4", "Accession": "5332" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FGA", "Accession": "2243" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CHMP4A", "Accession": "29082" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MBOAT7", "Accession": "79143" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PSCA", "Accession": "8000" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FNBP1L", "Accession": "54874" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RPS6KA2", "Accession": "6196" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SELE", "Accession": "6401" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SH3BGRL", "Accession": "6451" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "HNMT", "Accession": "3176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CHRDL1", "Accession": "91851" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "RAB31", "Accession": "11031" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ADK", "Accession": "132" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NEDD4L", "Accession": "23327" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "UBAP2L", "Accession": "9898" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KIF20A", "Accession": "10112" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CRYM", "Accession": "1428" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "BLVRB", "Accession": "645" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPOX", "Accession": "5498" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DDX3X", "Accession": "1654" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "WDR61", "Accession": "80349" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "MBNL1", "Accession": "4154" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GZMH", "Accession": "2999" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ELP1", "Accession": "8518" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PPP3CB", "Accession": "5532" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FOXA1", "Accession": "3169" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ANG", "Accession": "283" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC25A5", "Accession": "292" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGEF40", "Accession": "55701" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "EFHD2", "Accession": "79180" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SNX7", "Accession": "51375" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FMOD", "Accession": "2331" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "SLC33A1", "Accession": "9197" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FYB1", "Accession": "2533" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "PGM3", "Accession": "5238" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NCK1", "Accession": "4690" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "STAM", "Accession": "8027" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ASF1A", "Accession": "25842" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ORC1", "Accession": "4998" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "AOAH", "Accession": "313" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "ARHGAP12", "Accession": "94134" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "FUT1", "Accession": "2523" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "CHCHD7", "Accession": "79145" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "KCNAB2", "Accession": "8514" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "NSF", "Accession": "4905" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "DDB1", "Accession": "1642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_up", "Association_type": "genes" }, { "Term": [ { "Name": "GSN", "Accession": "2934" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCARB2", "Accession": "950" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SERINC3", "Accession": "10955" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGFBP2", "Accession": "3485" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYH10", "Accession": "4628" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZBTB18", "Accession": "10472" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TXNIP", "Accession": "10628" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AKR1C3", "Accession": "8644" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP3", "Accession": "1845" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MFSD10", "Accession": "10227" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRDX6", "Accession": "9588" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCNA1", "Accession": "8900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MAB21L2", "Accession": "10586" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTSB", "Accession": "1508" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SEL1L3", "Accession": "23231" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MXI1", "Accession": "4601" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TPBG", "Accession": "7162" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GUCY1A1", "Accession": "2982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CXCL14", "Accession": "9547" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NIBAN1", "Accession": "116496" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "WSB1", "Accession": "26118" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFITM1", "Accession": "8519" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LAPTM4B", "Accession": "55353" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZBTB38", "Accession": "253461" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCNJ15", "Accession": "3772" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPRY1", "Accession": "10252" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SYNE3", "Accession": "161176" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ID1", "Accession": "3397" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ECM1", "Accession": "1893" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SYNJ2", "Accession": "8871" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LTBP1", "Accession": "4052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL1A2", "Accession": "1278" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NRIP1", "Accession": "8204" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTGS1", "Accession": "5742" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DBNL", "Accession": "28988" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFRD2", "Accession": "7866" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KCTD12", "Accession": "115207" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRR7", "Accession": "80758" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLEC", "Accession": "5339" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BCL2A1", "Accession": "597" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRIM2", "Accession": "23321" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ENOPH1", "Accession": "58478" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CALB1", "Accession": "793" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ANXA4", "Accession": "307" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A1", "Accession": "6566" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACTG2", "Accession": "72" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GATM", "Accession": "2628" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PAX8", "Accession": "7849" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GRN", "Accession": "2896" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SFRP1", "Accession": "6422" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLN", "Accession": "5350" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HMGCS1", "Accession": "3157" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYH11", "Accession": "4629" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAV1", "Accession": "857" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTSH", "Accession": "1512" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLPBP", "Accession": "11212" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EFNB2", "Accession": "1948" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CTSZ", "Accession": "1522" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HPGD", "Accession": "3248" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SKP2", "Accession": "6502" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TPSB2", "Accession": "64499" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CA2", "Accession": "760" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TPSAB1", "Accession": "7177" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RBP1", "Accession": "5947" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RASSF2", "Accession": "9770" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MET", "Accession": "4233" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "INSIG1", "Accession": "3638" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DUSP5", "Accession": "1847" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MARCKSL1", "Accession": "65108" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SGK1", "Accession": "6446" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DPP4", "Accession": "1803" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AHCY", "Accession": "191" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FGFR3", "Accession": "2261" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IARS2", "Accession": "55699" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EREG", "Accession": "2069" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CALD1", "Accession": "800" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EIF1AY", "Accession": "9086" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DDX3Y", "Accession": "8653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPRR2B", "Accession": "6701" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NES", "Accession": "10763" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RPS4Y1", "Accession": "6192" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACP5", "Accession": "54" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CPA3", "Accession": "1359" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NANOG", "Accession": "79923" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "UGCG", "Accession": "7357" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MTCL1", "Accession": "23255" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPON1", "Accession": "10418" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HMOX1", "Accession": "3162" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AK4", "Accession": "205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HOMER3", "Accession": "9454" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTGIS", "Accession": "5740" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP6V0E1", "Accession": "8992" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SRSF10", "Accession": "10772" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BMP4", "Accession": "652" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RPL37A", "Accession": "6168" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "METAP1", "Accession": "23173" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCYL3", "Accession": "57147" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CADM1", "Accession": "23705" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "LGALS3", "Accession": "3958" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADH5", "Accession": "128" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PLAT", "Accession": "5327" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC16A3", "Accession": "9123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "S100A7", "Accession": "6278" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCNG2", "Accession": "901" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MREG", "Accession": "55686" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AQP1", "Accession": "358" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AKAP1", "Accession": "8165" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNFSF10", "Accession": "8743" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MALL", "Accession": "7851" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DCHS1", "Accession": "8642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CRIP1", "Accession": "1396" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MSMO1", "Accession": "6307" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CD9", "Accession": "928" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRAF4", "Accession": "9618" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MARCKS", "Accession": "4082" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CAPN3", "Accession": "825" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLV3-19", "Accession": "28797" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IGLJ3", "Accession": "28831" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTP4A3", "Accession": "11156" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "IFITM3", "Accession": "10410" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SYNM", "Accession": "23336" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM158", "Accession": "25907" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FBN2", "Accession": "2201" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF91", "Accession": "7644" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SCD", "Accession": "6319" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ANPEP", "Accession": "290" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "AMIGO2", "Accession": "347902" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MMP7", "Accession": "4316" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PTHLH", "Accession": "5744" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FGFR1", "Accession": "2260" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KDM5D", "Accession": "8284" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MXRA5", "Accession": "25878" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FRMD4B", "Accession": "23150" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ADA", "Accession": "100" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NET1", "Accession": "10276" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL6A1", "Accession": "1291" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TNPO1", "Accession": "3842" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRPF4", "Accession": "9128" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CYP51A1", "Accession": "1595" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NSG1", "Accession": "27065" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "KLK6", "Accession": "5653" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DARS1", "Accession": "1615" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CHAC1", "Accession": "79094" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FBXL12", "Accession": "54850" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF586", "Accession": "54807" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF589", "Accession": "51385" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FST", "Accession": "10468" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BNIP3L", "Accession": "665" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "RNASE1", "Accession": "6035" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SET", "Accession": "6418" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "DNAJB6", "Accession": "10049" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GRSF1", "Accession": "2926" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLAMF1", "Accession": "6504" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EIF5", "Accession": "1983" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TXN", "Accession": "7295" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ITM2C", "Accession": "81618" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "COL18A1", "Accession": "80781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TRAF5", "Accession": "7188" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TPP1", "Accession": "1200" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CHFR", "Accession": "55743" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZSCAN18", "Accession": "65982" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EPHB2", "Accession": "2048" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZDHHC6", "Accession": "64429" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "HSPA2", "Accession": "3306" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "G0S2", "Accession": "50486" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MITF", "Accession": "4286" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FKBP9", "Accession": "11328" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBX2", "Accession": "6909" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ATP2B1", "Accession": "490" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "FKSG49", "Accession": "400949" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CLIC4", "Accession": "25932" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EPHX1", "Accession": "2052" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CSNK1E", "Accession": "1454" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PRKCI", "Accession": "5584" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SPTAN1", "Accession": "6709" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "N4BP2L2", "Accession": "10443" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "BLMH", "Accession": "642" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SC5D", "Accession": "6309" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF264", "Accession": "9422" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF430", "Accession": "80264" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TKTL1", "Accession": "8277" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF512B", "Accession": "57473" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MGAT4B", "Accession": "11282" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EVI2A", "Accession": "2123" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TIMM8B", "Accession": "26521" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PDGFA", "Accession": "5154" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC25A16", "Accession": "8034" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "SLC38A1", "Accession": "81539" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "F3", "Accession": "2152" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF302", "Accession": "55900" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GATAD1", "Accession": "57798" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MYL9", "Accession": "10398" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ZNF266", "Accession": "10781" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "NFE2L1", "Accession": "4779" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ACP6", "Accession": "51205" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBC1D16", "Accession": "125058" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "CCNL2", "Accession": "81669" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "ST18", "Accession": "9705" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "UBE2H", "Accession": "7328" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "PDCD6", "Accession": "10016" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TUG1", "Accession": "55000" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "GPR37", "Accession": "2861" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "EFEMP2", "Accession": "30008" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MRPL57", "Accession": "78988" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "USP9Y", "Accession": "8287" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TMEM140", "Accession": "55281" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "TBCC", "Accession": "6903" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "MRM2", "Accession": "29960" } ], "Filename": "L1000FWD_signature_drugsetlibrary_down", "Association_type": "genes" }, { "Term": [ { "Name": "somnolence", "Accession": "C2830004" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "vomiting", "Accession": "C0042963" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "rash", "Accession": "C0015230" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "syncope", "Accession": "C0039070" } ], "Filename": "L1000FWD_predicted_side_effects", "Association_type": "side effects" }, { "Term": [ { "Name": "MACCS41", "Accession": "CTN" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS57", "Accession": "O HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS62", "Accession": "A$A!A$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS66", "Accession": "CC(C)(C)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS72", "Accession": "OAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS74", "Accession": "CH3ACH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS75", "Accession": "A!N$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS83", "Accession": "QAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS85", "Accession": "CN(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS91", "Accession": "QHAAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS92", "Accession": "OC(N)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS95", "Accession": "NAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS96", "Accession": "5M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS97", "Accession": "NAAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS98", "Accession": "QAAAAA@1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS100", "Accession": "ACH2N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS101", "Accession": "8M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS105", "Accession": "A$A($A)$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS110", "Accession": "NCO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS111", "Accession": "NACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS112", "Accession": "AA(A)(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS113", "Accession": "Onot%A%A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS117", "Accession": "NAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS118", "Accession": "ACH2CH2A > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS120", "Accession": "HETEROCYCLIC ATOM > 1 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS121", "Accession": "N HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS122", "Accession": "AN(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS127", "Accession": "A$A!O > 1 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS129", "Accession": "ACH2AACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS132", "Accession": "OACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS133", "Accession": "A$A!N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS137", "Accession": "HETEROCYCLE" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS139", "Accession": "OH" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS142", "Accession": "N > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS143", "Accession": "A$A!O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS144", "Accession": "Anot%A%Anot%A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS145", "Accession": "6M RING > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS146", "Accession": "O > 2" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS147", "Accession": "ACH2CH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS148", "Accession": "AQ(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS149", "Accession": "CH3 > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS150", "Accession": "A!A$A!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS152", "Accession": "OC(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS153", "Accession": "QCH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS154", "Accession": "C=O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS156", "Accession": "NA(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS157", "Accession": "C-O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS158", "Accession": "C-N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS159", "Accession": "O > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS160", "Accession": "CH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS161", "Accession": "N" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS162", "Accession": "AROMATIC" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS163", "Accession": "6M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS164", "Accession": "O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS165", "Accession": "RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "positive regulation of cell proliferation (GO:0008284)", "Accession": "GO:0008284" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "skin development (GO:0043588)", "Accession": "GO:0043588" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cell cycle (GO:0045786)", "Accession": "GO:0045786" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of transcription from RNA polymerase II promoter (GO:0045944)", "Accession": "GO:0045944" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of transcription, DNA-templated (GO:0045893)", "Accession": "GO:0045893" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of transcription from RNA polymerase II promoter (GO:0006357)", "Accession": "GO:0006357" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of epithelial cell proliferation (GO:0050680)", "Accession": "GO:0050680" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "response to tumor necrosis factor (GO:0034612)", "Accession": "GO:0034612" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" } ] }