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"L1000FWD_GO_Cellular_Component_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "extrinsic component of external side of plasma membrane (GO:0031232)", "Accession": "GO:0031232" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "MACCS34", "Accession": "CH2=A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS50", "Accession": "C=C(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS62", "Accession": "A$A!A$A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS76", "Accession": "C=C(A)A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS89", "Accession": "OAAAO" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS93", "Accession": "QCH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS99", "Accession": "C=C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS108", "Accession": "CH3AAACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS113", "Accession": "Onot%A%A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS115", "Accession": "CH3ACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS116", "Accession": "CH3AACH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS118", "Accession": "ACH2CH2A > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS126", "Accession": "A!O!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS127", "Accession": "A$A!O > 1 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS141", "Accession": "CH3 > 2 (&...)" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS143", "Accession": "A$A!O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS144", "Accession": "Anot%A%Anot%A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS145", "Accession": "6M RING > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS147", "Accession": "ACH2CH2A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS149", "Accession": "CH3 > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS150", "Accession": "A!A$A!A" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS152", "Accession": "OC(C)C" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS157", "Accession": "C-O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS159", "Accession": "O > 1" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS160", "Accession": "CH3" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS162", "Accession": "AROMATIC" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS163", "Accession": "6M RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS164", "Accession": "O" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "MACCS165", "Accession": "RING" } ], "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary", "Association_type": "chemical structure motifs" }, { "Term": [ { "Name": "neutrophil degranulation (GO:0043312)", "Accession": "GO:0043312" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "neutrophil activation involved in immune response (GO:0002283)", "Accession": "GO:0002283" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "neutrophil mediated immunity (GO:0002446)", "Accession": "GO:0002446" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of apoptotic process (GO:0043066)", "Accession": "GO:0043066" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of programmed cell death (GO:0043069)", "Accession": "GO:0043069" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of macromolecule metabolic process (GO:0010604)", "Accession": "GO:0010604" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "generation of neurons (GO:0048699)", "Accession": "GO:0048699" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of cellular process (GO:0048522)", "Accession": "GO:0048522" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of cell proliferation (GO:0042127)", "Accession": "GO:0042127" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of apoptotic process (GO:0042981)", "Accession": "GO:0042981" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of signal transduction (GO:0009966)", "Accession": "GO:0009966" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of endopeptidase activity (GO:0052548)", "Accession": "GO:0052548" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "cellular response to heat (GO:0034605)", "Accession": "GO:0034605" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of protein kinase B signaling (GO:0051896)", "Accession": "GO:0051896" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "positive regulation of interleukin-8 production (GO:0032757)", "Accession": "GO:0032757" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "extracellular matrix organization (GO:0030198)", "Accession": "GO:0030198" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cellular process (GO:0048523)", "Accession": "GO:0048523" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cell motility (GO:2000146)", "Accession": "GO:2000146" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "negative regulation of cell migration (GO:0030336)", "Accession": "GO:0030336" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "regulation of monocyte chemotaxis (GO:0090025)", "Accession": "GO:0090025" } ], "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "actin filament (GO:0005884)", "Accession": "GO:0005884" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "focal adhesion (GO:0005925)", "Accession": "GO:0005925" } ], "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up", "Association_type": "Gene Ontology terms" }, { "Term": [ { "Name": "Ferroptosis", "Accession": "map04216" } ], "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down", "Association_type": "KEGG pathways" } ] }