{
    "Entity": {
        "Name": "lylamine",
        "SMILES": "CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C",
        "Accession": "BRD-K62289640",
        "InChI_key": "JVVXZOOGOGPDRZ-SLFFLAALSA-N"
    },
    "Associations": [
        {
            "Term": [
                {
                    "Name": "MAPK signaling pathway",
                    "Accession": "map04010"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Protein processing in endoplasmic reticulum",
                    "Accession": "map04141"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Chronic myeloid leukemia",
                    "Accession": "map05220"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_up",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": ">= 4 H",
                    "Accession": "PubChem0"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 8 H",
                    "Accession": "PubChem1"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 16 H",
                    "Accession": "PubChem2"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 2 C",
                    "Accession": "PubChem9"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 4 C",
                    "Accession": "PubChem10"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 8 C",
                    "Accession": "PubChem11"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 16 C",
                    "Accession": "PubChem12"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 N",
                    "Accession": "PubChem14"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 any ring size 6",
                    "Accession": "PubChem178"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 saturated or aromatic carbon-only ring size 6",
                    "Accession": "PubChem179"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 2 any ring size 6",
                    "Accession": "PubChem185"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 2 saturated or aromatic carbon-only ring size 6",
                    "Accession": "PubChem186"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 3 any ring size 6",
                    "Accession": "PubChem192"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 3 saturated or aromatic carbon-only ring size 6",
                    "Accession": "PubChem193"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 any ring size 10",
                    "Accession": "PubChem248"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 saturated or aromatic carbon-only ring size 10",
                    "Accession": "PubChem249"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": ">= 1 aromatic ring",
                    "Accession": "PubChem255"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-H",
                    "Accession": "PubChem283"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C",
                    "Accession": "PubChem284"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-N",
                    "Accession": "PubChem285"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "N-H",
                    "Accession": "PubChem299"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~C)",
                    "Accession": "PubChem332"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~C)(~C)",
                    "Accession": "PubChem333"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~C)(~C)(~C)",
                    "Accession": "PubChem334"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~C)(~C)(~H)",
                    "Accession": "PubChem335"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~H)",
                    "Accession": "PubChem344"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~H)(~N)",
                    "Accession": "PubChem345"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(~N)",
                    "Accession": "PubChem351"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(:C)",
                    "Accession": "PubChem355"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~C)(:C)(:C)",
                    "Accession": "PubChem356"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~H)(~N)",
                    "Accession": "PubChem365"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~H)(:C)",
                    "Accession": "PubChem370"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~H)(:C)(:C)",
                    "Accession": "PubChem371"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(~H)(~H)(~H)",
                    "Accession": "PubChem374"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(:C)(:C)",
                    "Accession": "PubChem384"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "N(~C)(~H)",
                    "Accession": "PubChem393"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C=C",
                    "Accession": "PubChem416"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(-C)(-C)(=C)",
                    "Accession": "PubChem430"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(-C)(-H)(=C)",
                    "Accession": "PubChem434"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(-C)(=C)",
                    "Accession": "PubChem441"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C(-H)(=C)",
                    "Accession": "PubChem446"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C=C",
                    "Accession": "PubChem470"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C=C",
                    "Accession": "PubChem490"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "[#1]-C=C-[#1]",
                    "Accession": "PubChem516"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C=C-C:C",
                    "Accession": "PubChem520"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C=C-C",
                    "Accession": "PubChem524"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "[#1]-N-C-[#1]",
                    "Accession": "PubChem528"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C:C",
                    "Accession": "PubChem552"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C=C-C-C",
                    "Accession": "PubChem556"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C=C-C=C",
                    "Accession": "PubChem564"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C-C",
                    "Accession": "PubChem570"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C:C-C:C",
                    "Accession": "PubChem578"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C-C",
                    "Accession": "PubChem582"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C=C-C",
                    "Accession": "PubChem584"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "N-C-C-C-C",
                    "Accession": "PubChem592"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C-C-C",
                    "Accession": "PubChem595"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "[#1]-C-C=C-[#1]",
                    "Accession": "PubChem599"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C:C:C-C",
                    "Accession": "PubChem603"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C:C",
                    "Accession": "PubChem608"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C:C-C-C:C",
                    "Accession": "PubChem618"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C:C-C",
                    "Accession": "PubChem634"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C=C-C-C-C",
                    "Accession": "PubChem640"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C=C-C-C",
                    "Accession": "PubChem660"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C=C-C=C",
                    "Accession": "PubChem664"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C:C-C-C",
                    "Accession": "PubChem668"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C=C-C:C",
                    "Accession": "PubChem677"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C=C-C",
                    "Accession": "PubChem678"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C-C-C",
                    "Accession": "PubChem679"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "N-C-C-C-C-C",
                    "Accession": "PubChem683"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C-C-C-C",
                    "Accession": "PubChem688"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C-C-C-C-C",
                    "Accession": "PubChem696"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C-C-C-C(C)-C",
                    "Accession": "PubChem697"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C(C)-C-C",
                    "Accession": "PubChem708"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C(C)-C-C-C",
                    "Accession": "PubChem709"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C-C(C)-C-C",
                    "Accession": "PubChem710"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C(C)(C)-C-C",
                    "Accession": "PubChem711"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "C-C(C)-C(C)-C",
                    "Accession": "PubChem712"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "Cc1ccc(C)cc1",
                    "Accession": "PubChem713"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "Cc1cc(C)ccc1",
                    "Accession": "PubChem734"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "Cc1c(C)cccc1",
                    "Accession": "PubChem755"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "CC1CCC(C)CC1",
                    "Accession": "PubChem776"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "CC1CC(C)CCC1",
                    "Accession": "PubChem797"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "CC1C(C)CCCC1",
                    "Accession": "PubChem818"
                }
            ],
            "Filename": "PubChem_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)",
                    "Accession": "GO:0016616"
                }
            ],
            "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "CPM",
                    "Accession": "1368"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LY96",
                    "Accession": "23643"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GADD45B",
                    "Accession": "4616"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CCNL1",
                    "Accession": "57018"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SOD2",
                    "Accession": "6648"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SNAI2",
                    "Accession": "6591"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEC62",
                    "Accession": "7095"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TMEM45A",
                    "Accession": "55076"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CYTIP",
                    "Accession": "9595"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSGALNACT1",
                    "Accession": "55790"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HES1",
                    "Accession": "3280"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MUC5B",
                    "Accession": "727897"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ADM",
                    "Accession": "133"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL8",
                    "Accession": "3576"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF5",
                    "Accession": "1983"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AGR2",
                    "Accession": "10551"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UPF3A",
                    "Accession": "65110"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IFRD1",
                    "Accession": "3475"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KLF4",
                    "Accession": "9314"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARHGAP29",
                    "Accession": "9411"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BHLHE41",
                    "Accession": "79365"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZBTB18",
                    "Accession": "10472"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FOSB",
                    "Accession": "2354"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ADGRG2",
                    "Accession": "10149"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CYP1B1",
                    "Accession": "1545"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RCBTB2",
                    "Accession": "1102"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSNK1D",
                    "Accession": "1453"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FNDC3B",
                    "Accession": "64778"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TFPI2",
                    "Accession": "7980"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TNPO1",
                    "Accession": "3842"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "YBX3",
                    "Accession": "8531"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IGHM",
                    "Accession": "3507"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PEG10",
                    "Accession": "23089"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TIPARP",
                    "Accession": "25976"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "JMJD6",
                    "Accession": "23210"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GALNT7",
                    "Accession": "51809"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AZGP1",
                    "Accession": "563"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PPP2R5E",
                    "Accession": "5529"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GREB1",
                    "Accession": "9687"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZHX2",
                    "Accession": "22882"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SFRP4",
                    "Accession": "6424"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SAT1",
                    "Accession": "6303"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ANKRD10",
                    "Accession": "55608"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SERPINA3",
                    "Accession": "12"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MSX1",
                    "Accession": "4487"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IGHD",
                    "Accession": "3495"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HSPA13",
                    "Accession": "6782"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FKBP11",
                    "Accession": "51303"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NAMPT",
                    "Accession": "10135"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NPTX2",
                    "Accession": "4885"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CTH",
                    "Accession": "1491"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC7A11",
                    "Accession": "23657"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEL1L3",
                    "Accession": "23231"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KLF10",
                    "Accession": "7071"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZNF91",
                    "Accession": "7644"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SSR1",
                    "Accession": "6745"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MAFF",
                    "Accession": "23764"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MYC",
                    "Accession": "4609"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC7A1",
                    "Accession": "6541"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DDIT4",
                    "Accession": "54541"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ASNS",
                    "Accession": "440"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRIB3",
                    "Accession": "57761"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EGR1",
                    "Accession": "1958"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KDM3A",
                    "Accession": "55818"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IGFBP5",
                    "Accession": "3488"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PTX3",
                    "Accession": "5806"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IFI16",
                    "Accession": "3428"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ICAM1",
                    "Accession": "3383"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MSLN",
                    "Accession": "10232"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZFP36",
                    "Accession": "7538"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD55",
                    "Accession": "1604"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DDIT3",
                    "Accession": "1649"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HERPUD1",
                    "Accession": "9709"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COL6A2",
                    "Accession": "1292"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IER3",
                    "Accession": "8870"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ATF3",
                    "Accession": "467"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PLK2",
                    "Accession": "10769"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TPBG",
                    "Accession": "7162"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GADD45A",
                    "Accession": "1647"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PTP4A1",
                    "Accession": "7803"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MBNL2",
                    "Accession": "10150"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BAZ1A",
                    "Accession": "11177"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PROM1",
                    "Accession": "8842"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "STK17A",
                    "Accession": "9263"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CLDN3",
                    "Accession": "1365"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HMOX1",
                    "Accession": "3162"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AREG",
                    "Accession": "374"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DUSP1",
                    "Accession": "1843"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RSL1D1",
                    "Accession": "26156"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IRS2",
                    "Accession": "8660"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "E2F2",
                    "Accession": "1870"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IER5",
                    "Accession": "51278"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC1A4",
                    "Accession": "6509"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MFAP5",
                    "Accession": "8076"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ATP1B1",
                    "Accession": "481"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZFAND5",
                    "Accession": "7763"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARC",
                    "Accession": "23237"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TGFA",
                    "Accession": "7039"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZIC1",
                    "Accession": "7545"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TXNRD1",
                    "Accession": "7296"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FOS",
                    "Accession": "2353"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SIK1",
                    "Accession": "150094"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IGFBP3",
                    "Accession": "3486"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "S100P",
                    "Accession": "6286"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DUSP5",
                    "Accession": "1847"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RIOK3",
                    "Accession": "8780"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PPP1R15A",
                    "Accession": "23645"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HSPA6",
                    "Accession": "3310"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HSPA1A",
                    "Accession": "3303"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RNMT",
                    "Accession": "8731"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NR4A2",
                    "Accession": "4929"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NR4A1",
                    "Accession": "3164"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GCLM",
                    "Accession": "2730"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TGFBI",
                    "Accession": "7045"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ATF4",
                    "Accession": "468"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TSPAN12",
                    "Accession": "23554"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LARP6",
                    "Accession": "55323"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KRT23",
                    "Accession": "25984"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UGCG",
                    "Accession": "7357"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CHN2",
                    "Accession": "1124"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SCNN1A",
                    "Accession": "6337"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NRN1",
                    "Accession": "51299"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARFGEF1",
                    "Accession": "10565"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD44",
                    "Accession": "960"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NRIP1",
                    "Accession": "8204"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TMEM100",
                    "Accession": "55273"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "N4BP2L2",
                    "Accession": "10443"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KLK6",
                    "Accession": "5653"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "WSB1",
                    "Accession": "26118"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC2A3",
                    "Accession": "6515"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "STC2",
                    "Accession": "8614"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ASPN",
                    "Accession": "54829"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RBM3",
                    "Accession": "5935"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PLIN2",
                    "Accession": "123"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PCSK1",
                    "Accession": "5122"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "WIPI1",
                    "Accession": "55062"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TSPAN5",
                    "Accession": "10098"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LAPTM5",
                    "Accession": "7805"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "STC1",
                    "Accession": "6781"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RCN1",
                    "Accession": "5954"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DCLK1",
                    "Accession": "9201"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SST",
                    "Accession": "6750"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DDX21",
                    "Accession": "9188"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NR3C1",
                    "Accession": "2908"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF3A",
                    "Accession": "8661"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SERP1",
                    "Accession": "27230"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NUCB2",
                    "Accession": "4925"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GOLGA8A",
                    "Accession": "23015"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GALNT3",
                    "Accession": "2591"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GFPT1",
                    "Accession": "2673"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DNAJB9",
                    "Accession": "4189"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEL1L",
                    "Accession": "6400"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SERPINA1",
                    "Accession": "5265"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DNAJC10",
                    "Accession": "54431"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DARS1",
                    "Accession": "1615"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NNMT",
                    "Accession": "4837"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TFF3",
                    "Accession": "7033"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PRDX4",
                    "Accession": "10549"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CPD",
                    "Accession": "1362"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LRRC17",
                    "Accession": "10234"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ING3",
                    "Accession": "54556"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TNFAIP6",
                    "Accession": "7130"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COBL",
                    "Accession": "23242"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRD",
                    "Accession": "6964"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GLRX",
                    "Accession": "2745"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC19A2",
                    "Accession": "10560"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TAF1D",
                    "Accession": "79101"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CAPN2",
                    "Accession": "824"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MAGED1",
                    "Accession": "9500"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TLK2",
                    "Accession": "11011"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FIS1",
                    "Accession": "51024"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COL1A1",
                    "Accession": "1277"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RYBP",
                    "Accession": "23429"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC2A1",
                    "Accession": "6513"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF2AK3",
                    "Accession": "9451"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC25A36",
                    "Accession": "55186"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NT5E",
                    "Accession": "4907"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MAN1A1",
                    "Accession": "4121"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "VEGFA",
                    "Accession": "7422"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RLF",
                    "Accession": "6018"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEC61G",
                    "Accession": "23480"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NFIL3",
                    "Accession": "4783"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EGR3",
                    "Accession": "1960"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LIF",
                    "Accession": "3976"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GEM",
                    "Accession": "2669"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NFKBIA",
                    "Accession": "4792"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DUSP4",
                    "Accession": "1846"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF1B",
                    "Accession": "10289"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SPON2",
                    "Accession": "10417"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC16A6",
                    "Accession": "9120"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRDV3",
                    "Accession": "28516"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TOMM20",
                    "Accession": "9804"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CDK6",
                    "Accession": "1021"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TNFRSF21",
                    "Accession": "27242"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "OPN3",
                    "Accession": "23596"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PEG3",
                    "Accession": "5178"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UAP1",
                    "Accession": "6675"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SH3YL1",
                    "Accession": "26751"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PDGFC",
                    "Accession": "56034"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DNAJC2",
                    "Accession": "27000"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KRIT1",
                    "Accession": "889"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "APOLD1",
                    "Accession": "81575"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MYB",
                    "Accession": "4602"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CRK",
                    "Accession": "1398"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PAEP",
                    "Accession": "5047"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HNRNPDL",
                    "Accession": "9987"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF1",
                    "Accession": "10209"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TBC1D31",
                    "Accession": "93594"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRAM1",
                    "Accession": "23471"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AKAP9",
                    "Accession": "10142"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RABGGTB",
                    "Accession": "5876"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CEP57",
                    "Accession": "9702"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GATAD1",
                    "Accession": "57798"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HECA",
                    "Accession": "51696"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TMEM87A",
                    "Accession": "25963"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CPB1",
                    "Accession": "1360"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UFM1",
                    "Accession": "51569"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "WDR13",
                    "Accession": "64743"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FAP",
                    "Accession": "2191"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NBPF10",
                    "Accession": "100132406"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CDV3",
                    "Accession": "55573"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CLPX",
                    "Accession": "10845"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HNRNPA1",
                    "Accession": "3178"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NOTCH2NLB",
                    "Accession": "100996763"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TIMM9",
                    "Accession": "26520"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARFGAP3",
                    "Accession": "26286"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TAC1",
                    "Accession": "6863"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HMGB2",
                    "Accession": "3148"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARHGEF2",
                    "Accession": "9181"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEC24D",
                    "Accession": "9871"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSGALNACT2",
                    "Accession": "55454"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SON",
                    "Accession": "6651"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FAM3C",
                    "Accession": "10447"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FNDC3A",
                    "Accession": "22862"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RSRC2",
                    "Accession": "65117"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRIB1",
                    "Accession": "10221"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ADAM9",
                    "Accession": "8754"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARF4",
                    "Accession": "378"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RBM39",
                    "Accession": "9584"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RNF6",
                    "Accession": "6049"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TVP23B",
                    "Accession": "51030"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AVL9",
                    "Accession": "23080"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MED13",
                    "Accession": "9969"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SEC31A",
                    "Accession": "22872"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CDK7",
                    "Accession": "1022"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CHMP2B",
                    "Accession": "25978"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EDEM3",
                    "Accession": "80267"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARCN1",
                    "Accession": "372"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TAF9",
                    "Accession": "6880"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GNL2",
                    "Accession": "29889"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FNBP4",
                    "Accession": "23360"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GOLGA5",
                    "Accession": "9950"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KBTBD2",
                    "Accession": "25948"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC30A5",
                    "Accession": "64924"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_up",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PDLIM7",
                    "Accession": "9260"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EIF5A",
                    "Accession": "1984"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NYNRIN",
                    "Accession": "57523"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CYP4B1",
                    "Accession": "1580"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PRAME",
                    "Accession": "23532"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COQ8A",
                    "Accession": "56997"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CKB",
                    "Accession": "1152"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NQO1",
                    "Accession": "1728"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MS4A1",
                    "Accession": "931"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL14",
                    "Accession": "9547"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL9",
                    "Accession": "4283"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CCL19",
                    "Accession": "6363"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LAPTM4B",
                    "Accession": "55353"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SPRR1A",
                    "Accession": "6698"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MT1E",
                    "Accession": "4493"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COL4A6",
                    "Accession": "1288"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COL4A5",
                    "Accession": "1287"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GJA1",
                    "Accession": "2697"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD52",
                    "Accession": "1043"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FABP5",
                    "Accession": "2171"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MAGEA3",
                    "Accession": "4102"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MAGEA6",
                    "Accession": "4105"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RGS5",
                    "Accession": "8490"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SPINK5",
                    "Accession": "11005"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ABCC6",
                    "Accession": "368"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PTGS1",
                    "Accession": "5742"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD24",
                    "Accession": "100133941"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TMEM47",
                    "Accession": "83604"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GPX2",
                    "Accession": "2877"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MECOM",
                    "Accession": "2122"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CLU",
                    "Accession": "1191"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "VAMP3",
                    "Accession": "9341"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AHNAK2",
                    "Accession": "113146"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL10",
                    "Accession": "3627"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TSPYL5",
                    "Accession": "85453"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSRP1",
                    "Accession": "1465"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IGL",
                    "Accession": "3535"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KRT5",
                    "Accession": "3852"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HMGCS1",
                    "Accession": "3157"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL11",
                    "Accession": "6373"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MYH11",
                    "Accession": "4629"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CALM1",
                    "Accession": "801"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SNN",
                    "Accession": "8303"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SFN",
                    "Accession": "2810"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IFIT1",
                    "Accession": "3434"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HPGD",
                    "Accession": "3248"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NME4",
                    "Accession": "4833"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DBI",
                    "Accession": "1622"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CCNF",
                    "Accession": "899"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COL3A1",
                    "Accession": "1281"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KCNMA1",
                    "Accession": "3778"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PWP1",
                    "Accession": "11137"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KRT13",
                    "Accession": "3860"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FASN",
                    "Accession": "2194"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RRM2",
                    "Accession": "6241"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IDH2",
                    "Accession": "3418"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MCM6",
                    "Accession": "4175"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AHCY",
                    "Accession": "191"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "B4GAT1",
                    "Accession": "11041"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FGFR3",
                    "Accession": "2261"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "THBS1",
                    "Accession": "7057"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DDC",
                    "Accession": "1644"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FLNB",
                    "Accession": "2317"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GSTM3",
                    "Accession": "2947"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC5A6",
                    "Accession": "8884"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CALD1",
                    "Accession": "800"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TM7SF2",
                    "Accession": "7108"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NPEPL1",
                    "Accession": "79716"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXCL13",
                    "Accession": "10563"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC27A2",
                    "Accession": "11001"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD59",
                    "Accession": "966"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GAL",
                    "Accession": "51083"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BEX3",
                    "Accession": "27018"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TSPAN4",
                    "Accession": "7106"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EFEMP1",
                    "Accession": "2202"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PRKAR2B",
                    "Accession": "5577"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NLRP2",
                    "Accession": "55655"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "S100A8",
                    "Accession": "6279"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NTS",
                    "Accession": "4922"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "AK4",
                    "Accession": "205"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DKK1",
                    "Accession": "22943"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BMP4",
                    "Accession": "652"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FLNA",
                    "Accession": "2316"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ADH5",
                    "Accession": "128"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MATN2",
                    "Accession": "4147"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PEBP1",
                    "Accession": "5037"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IFIT5",
                    "Accession": "24138"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ISG15",
                    "Accession": "9636"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NUTF2",
                    "Accession": "10204"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "S100A7",
                    "Accession": "6278"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NDUFA3",
                    "Accession": "4696"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IFI6",
                    "Accession": "2537"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ALDH1A3",
                    "Accession": "220"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HMG20B",
                    "Accession": "10362"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PTGDS",
                    "Accession": "5730"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LAP3",
                    "Accession": "51056"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GALNT11",
                    "Accession": "63917"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ITGB1BP1",
                    "Accession": "9270"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MREG",
                    "Accession": "55686"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SP110",
                    "Accession": "3431"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MALL",
                    "Accession": "7851"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SELENOW",
                    "Accession": "6415"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CD9",
                    "Accession": "928"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "DCXR",
                    "Accession": "51181"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NRIP3",
                    "Accession": "56675"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "IL1RN",
                    "Accession": "3557"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSTA",
                    "Accession": "1475"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CTTN",
                    "Accession": "2017"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CYFIP1",
                    "Accession": "23191"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "YWHAB",
                    "Accession": "7529"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SYNM",
                    "Accession": "23336"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ANGPT1",
                    "Accession": "284"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "POLR2I",
                    "Accession": "5438"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TFAP2B",
                    "Accession": "7021"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SPR",
                    "Accession": "6697"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TUBA1A",
                    "Accession": "7846"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GBP1",
                    "Accession": "2633"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UCHL1",
                    "Accession": "7345"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ME1",
                    "Accession": "4199"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "STOM",
                    "Accession": "2040"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CSF2RB",
                    "Accession": "1439"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "C7",
                    "Accession": "730"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FPGS",
                    "Accession": "2356"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TRIP13",
                    "Accession": "9319"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "QDPR",
                    "Accession": "5860"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SORD",
                    "Accession": "6652"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ZNF185",
                    "Accession": "7739"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SLC25A1",
                    "Accession": "6576"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "JUP",
                    "Accession": "3728"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PFKL",
                    "Accession": "5211"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SUMO1",
                    "Accession": "7341"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARPC4",
                    "Accession": "10093"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SRC",
                    "Accession": "6714"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BAD",
                    "Accession": "572"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BIK",
                    "Accession": "638"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GSTP1",
                    "Accession": "2950"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SRSF6",
                    "Accession": "6431"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ILK",
                    "Accession": "3611"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CXADR",
                    "Accession": "1525"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CETN2",
                    "Accession": "1069"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ATOX1",
                    "Accession": "475"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MTRNR2L1",
                    "Accession": "100462977"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LAGE3",
                    "Accession": "8270"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BIRC5",
                    "Accession": "332"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ADAMDEC1",
                    "Accession": "27299"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CLC",
                    "Accession": "1178"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EPB41L4B",
                    "Accession": "54566"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ATP6V0E2",
                    "Accession": "155066"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PGAM1",
                    "Accession": "5223"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ARF3",
                    "Accession": "377"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "KRT4",
                    "Accession": "3851"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TMEM14A",
                    "Accession": "28978"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SCPEP1",
                    "Accession": "59342"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TAX1BP3",
                    "Accession": "30851"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PCCB",
                    "Accession": "5096"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GPD1L",
                    "Accession": "23171"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ACSF2",
                    "Accession": "80221"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MSRB2",
                    "Accession": "22921"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "POLR2L",
                    "Accession": "5441"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RRP8",
                    "Accession": "23378"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GINS2",
                    "Accession": "51659"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "SNRNP25",
                    "Accession": "79622"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "POLE2",
                    "Accession": "5427"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "BDH1",
                    "Accession": "622"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ESRP2",
                    "Accession": "80004"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CES2",
                    "Accession": "8824"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CHRNA3",
                    "Accession": "1136"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MYBL2",
                    "Accession": "4605"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FXYD2",
                    "Accession": "486"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ALDH3B2",
                    "Accession": "222"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ACOT7",
                    "Accession": "11332"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FAM162A",
                    "Accession": "26355"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RRAS",
                    "Accession": "6237"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "PAFAH1B3",
                    "Accession": "5050"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LSS",
                    "Accession": "4047"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GOT2",
                    "Accession": "2806"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "WDR61",
                    "Accession": "80349"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MYCBP",
                    "Accession": "26292"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TP63",
                    "Accession": "8626"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "MDH1",
                    "Accession": "4190"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "GABRE",
                    "Accession": "2564"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NACC2",
                    "Accession": "138151"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "RALGDS",
                    "Accession": "5900"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ECHS1",
                    "Accession": "1892"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UNG",
                    "Accession": "7374"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UBL5",
                    "Accession": "59286"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CARHSP1",
                    "Accession": "23589"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ASF1B",
                    "Accession": "55723"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "STX7",
                    "Accession": "8417"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "ALDH7A1",
                    "Accession": "501"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "COX5B",
                    "Accession": "1329"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CBX6",
                    "Accession": "23466"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "FAH",
                    "Accession": "2184"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CAPN1",
                    "Accession": "823"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "EPPK1",
                    "Accession": "83481"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TSPYL4",
                    "Accession": "23270"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "LIG1",
                    "Accession": "3978"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "UBE2N",
                    "Accession": "7334"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "HIBCH",
                    "Accession": "26275"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "CYB5B",
                    "Accession": "80777"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "TUFM",
                    "Accession": "7284"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "NDUFA2",
                    "Accession": "4695"
                }
            ],
            "Filename": "L1000FWD_signature_drugsetlibrary_down",
            "Association_type": "genes"
        },
        {
            "Term": [
                {
                    "Name": "transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0000982)",
                    "Accession": "GO:0000982"
                }
            ],
            "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "transcription regulatory region DNA binding (GO:0044212)",
                    "Accession": "GO:0044212"
                }
            ],
            "Filename": "L1000FWD_GO_Molecular_Function_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "cough",
                    "Accession": "C0010200"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "back pain",
                    "Accession": "C0004604"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "vomiting",
                    "Accession": "C0042963"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "myalgia",
                    "Accession": "C0231528"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "dermatitis",
                    "Accession": "C0011603"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "fatigue",
                    "Accession": "C0015672"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "hypertension",
                    "Accession": "C0020538"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "dyspepsia",
                    "Accession": "C0013395"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "alopecia",
                    "Accession": "C0002170"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "pruritus",
                    "Accession": "C0033774"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "haemorrhage",
                    "Accession": "C0019080"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "flushing",
                    "Accession": "C0016382"
                }
            ],
            "Filename": "L1000FWD_predicted_side_effects",
            "Association_type": "side effects"
        },
        {
            "Term": [
                {
                    "Name": "intermediate filament (GO:0005882)",
                    "Accession": "GO:0005882"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "cytoskeleton (GO:0005856)",
                    "Accession": "GO:0005856"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "focal adhesion (GO:0005925)",
                    "Accession": "GO:0005925"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "keratin filament (GO:0045095)",
                    "Accession": "GO:0045095"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "mitochondrion (GO:0005739)",
                    "Accession": "GO:0005739"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "MACCS66",
                    "Accession": "CC(C)(C)A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS74",
                    "Accession": "CH3ACH3"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS82",
                    "Accession": "ACH2QH"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS84",
                    "Accession": "NH2"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS90",
                    "Accession": "QHAACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS91",
                    "Accession": "QHAAACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS100",
                    "Accession": "ACH2N"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS101",
                    "Accession": "8M RING"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS105",
                    "Accession": "A$A($A)$A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS108",
                    "Accession": "CH3AAACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS112",
                    "Accession": "AA(A)(A)A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS115",
                    "Accession": "CH3ACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS116",
                    "Accession": "CH3AACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS118",
                    "Accession": "ACH2CH2A > 1"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS128",
                    "Accession": "ACH2AAACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS129",
                    "Accession": "ACH2AACH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS141",
                    "Accession": "CH3 > 2 (&...)"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS144",
                    "Accession": "Anot%A%Anot%A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS145",
                    "Accession": "6M RING > 1"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS147",
                    "Accession": "ACH2CH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS149",
                    "Accession": "CH3 > 1"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS151",
                    "Accession": "NH"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS153",
                    "Accession": "QCH2A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS155",
                    "Accession": "A!CH2!A"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS158",
                    "Accession": "C-N"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS160",
                    "Accession": "CH3"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS161",
                    "Accession": "N"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS162",
                    "Accession": "AROMATIC"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS163",
                    "Accession": "6M RING"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "MACCS165",
                    "Accession": "RING"
                }
            ],
            "Filename": "RDKIT_maccs_fingerprints_drugsetlibrary",
            "Association_type": "chemical structure motifs"
        },
        {
            "Term": [
                {
                    "Name": "negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154)",
                    "Accession": "GO:0043154"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of intracellular signal transduction (GO:1902533)",
                    "Accession": "GO:1902533"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of chemotaxis (GO:0050921)",
                    "Accession": "GO:0050921"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "glucose metabolic process (GO:0006006)",
                    "Accession": "GO:0006006"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "hexose biosynthetic process (GO:0019319)",
                    "Accession": "GO:0019319"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_down",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "regulation of apoptotic process (GO:0042981)",
                    "Accession": "GO:0042981"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of transcription from RNA polymerase II promoter (GO:0045944)",
                    "Accession": "GO:0045944"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of transcription, DNA-templated (GO:0045893)",
                    "Accession": "GO:0045893"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "regulation of transcription from RNA polymerase II promoter (GO:0006357)",
                    "Accession": "GO:0006357"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "negative regulation of transcription from RNA polymerase II promoter (GO:0000122)",
                    "Accession": "GO:0000122"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "PERK-mediated unfolded protein response (GO:0036499)",
                    "Accession": "GO:0036499"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "response to endoplasmic reticulum stress (GO:0034976)",
                    "Accession": "GO:0034976"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "IRE1-mediated unfolded protein response (GO:0036498)",
                    "Accession": "GO:0036498"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of gene expression (GO:0010628)",
                    "Accession": "GO:0010628"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "positive regulation of apoptotic process (GO:0043065)",
                    "Accession": "GO:0043065"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)",
                    "Accession": "GO:0070059"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "endothelial cell migration (GO:0043542)",
                    "Accession": "GO:0043542"
                }
            ],
            "Filename": "L1000FWD_GO_Biological_Processes_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)",
                    "Accession": "GO:0005793"
                }
            ],
            "Filename": "L1000FWD_GO_Cellular_Component_drugsetlibrary_up",
            "Association_type": "Gene Ontology terms"
        },
        {
            "Term": [
                {
                    "Name": "beta-Alanine metabolism",
                    "Accession": "map00410"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Glycolysis / Gluconeogenesis",
                    "Accession": "map00010"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Valine, leucine and isoleucine degradation",
                    "Accession": "map00280"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Glutathione metabolism",
                    "Accession": "map00480"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Drug metabolism",
                    "Accession": "map00982"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Tyrosine metabolism",
                    "Accession": "map00350"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        },
        {
            "Term": [
                {
                    "Name": "Phenylalanine metabolism",
                    "Accession": "map00360"
                }
            ],
            "Filename": "L1000FWD_KEGG_Pathways_drugsetlibrary_down",
            "Association_type": "KEGG pathways"
        }
    ]
}